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RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia.
Lipka DB, Witte T, Toth R, Yang J, Wiesenfarth M, Nöllke P, Fischer A, Brocks D, Gu Z, Park J, Strahm B, Wlodarski M, Yoshimi A, Claus R, Lübbert M, Busch H, Boerries M, Hartmann M, Schönung M, Kilik U, Langstein J, Wierzbinska JA, Pabst C, Garg S, Catalá A, De Moerloose B, Dworzak M, Hasle H, Locatelli F, Masetti R, Schmugge M, Smith O, Stary J, Ussowicz M, van den Heuvel-Eibrink MM, Assenov Y, Schlesner M, Niemeyer C, Flotho C, Plass C. Lipka DB, et al. Among authors: hartmann m. Nat Commun. 2017 Dec 19;8(1):2126. doi: 10.1038/s41467-017-02177-w. Nat Commun. 2017. PMID: 29259247 Free PMC article. Clinical Trial.
Reactivation of endogenous retroviral elements via treatment with DNMT- and HDAC-inhibitors.
Daskalakis M, Brocks D, Sheng YH, Islam MS, Ressnerova A, Assenov Y, Milde T, Oehme I, Witt O, Goyal A, Kühn A, Hartmann M, Weichenhan D, Jung M, Plass C. Daskalakis M, et al. Among authors: hartmann m. Cell Cycle. 2018;17(7):811-822. doi: 10.1080/15384101.2018.1442623. Epub 2018 Apr 30. Cell Cycle. 2018. PMID: 29633898 Free PMC article. Review.
Globally altered epigenetic landscape and delayed osteogenic differentiation in H3.3-G34W-mutant giant cell tumor of bone.
Lutsik P, Baude A, Mancarella D, Öz S, Kühn A, Toth R, Hey J, Toprak UH, Lim J, Nguyen VH, Jiang C, Mayakonda A, Hartmann M, Rosemann F, Breuer K, Vonficht D, Grünschläger F, Lee S, Schuhmacher MK, Kusevic D, Jauch A, Weichenhan D, Zustin J, Schlesner M, Haas S, Park JH, Park YJ, Oppermann U, Jeltsch A, Haller F, Fellenberg J, Lindroth AM, Plass C. Lutsik P, et al. Among authors: hartmann m. Nat Commun. 2020 Oct 27;11(1):5414. doi: 10.1038/s41467-020-18955-y. Nat Commun. 2020. PMID: 33110075 Free PMC article.
International Consensus Definition of DNA Methylation Subgroups in Juvenile Myelomonocytic Leukemia.
Schönung M, Meyer J, Nöllke P, Olshen AB, Hartmann M, Murakami N, Wakamatsu M, Okuno Y, Plass C, Loh ML, Niemeyer CM, Muramatsu H, Flotho C, Stieglitz E, Lipka DB. Schönung M, et al. Among authors: hartmann m. Clin Cancer Res. 2021 Jan 1;27(1):158-168. doi: 10.1158/1078-0432.CCR-20-3184. Epub 2020 Nov 2. Clin Cancer Res. 2021. PMID: 33139265 Free PMC article.
The age of the bone marrow microenvironment influences B-cell acute lymphoblastic leukemia progression via CXCR5-CXCL13.
Zanetti C, Kumar R, Ender J, Godavarthy PS, Hartmann M, Hey J, Breuer K, Weissenberger ES, Minciacchi VR, Karantanou C, Gu Z, Roberts KG, Metzler M, Stock W, Mullighan CG, Bloomfield CD, Filmann N, Bankov K, Hartmann S, Hasserjian RP, Cousins AF, Halsey C, Plass C, Lipka DB, Krause DS. Zanetti C, et al. Among authors: hartmann s, hartmann m. Blood. 2021 Nov 11;138(19):1870-1884. doi: 10.1182/blood.2021011557. Blood. 2021. PMID: 34424946 Free PMC article.
Dynamic DNA methylation reveals novel cis-regulatory elements in mouse hematopoiesis.
Schönung M, Hartmann M, Krämer S, Stäble S, Hakobyan M, Kleinert E, Aurich T, Cobanoglu D, Heidel FH, Fröhling S, Milsom MD, Schlesner M, Lutsik P, Lipka DB. Schönung M, et al. Among authors: hartmann m. Exp Hematol. 2023 Jan;117:24-42.e7. doi: 10.1016/j.exphem.2022.11.001. Epub 2022 Nov 8. Exp Hematol. 2023. PMID: 36368558
Multi-omic and functional analysis for classification and treatment of sarcomas with FUS-TFCP2 or EWSR1-TFCP2 fusions.
Schöpf J, Uhrig S, Heilig CE, Lee KS, Walther T, Carazzato A, Dobberkau AM, Weichenhan D, Plass C, Hartmann M, Diwan GD, Carrero ZI, Ball CR, Hohl T, Kindler T, Rudolph-Hähnel P, Helm D, Schneider M, Nilsson A, Øra I, Imle R, Banito A, Russell RB, Jones BC, Lipka DB, Glimm H, Hübschmann D, Hartmann W, Fröhling S, Scholl C. Schöpf J, et al. Among authors: hartmann w, hartmann m. Nat Commun. 2024 Jan 2;15(1):51. doi: 10.1038/s41467-023-44360-2. Nat Commun. 2024. PMID: 38168093 Free PMC article.
1,961 results