Hastings ML - Search Results

1

Induction of antagonistic soluble decoy receptor tyrosine kinases by intronic polyA activation.

Vorlová S, Rocco G, Lefave CV, Jodelka FM, Hess K, Hastings ML, Henke E, Cartegni L. Vorlová S, et al. Among authors: hastings ml. Mol Cell. 2011 Sep 16;43(6):927-39. doi: 10.1016/j.molcel.2011.08.009. Mol Cell. 2011. PMID: 21925381 Free PMC article.

2

A feedback loop regulates splicing of the spinal muscular atrophy-modifying gene, SMN2.

Jodelka FM, Ebert AD, Duelli DM, Hastings ML. Jodelka FM, et al. Among authors: hastings ml. Hum Mol Genet. 2010 Dec 15;19(24):4906-17. doi: 10.1093/hmg/ddq425. Epub 2010 Sep 30. Hum Mol Genet. 2010. PMID: 20884664 Free PMC article.

3

Therapeutic correction of ApoER2 splicing in Alzheimer's disease mice using antisense oligonucleotides.

Hinrich AJ, Jodelka FM, Chang JL, Brutman D, Bruno AM, Briggs CA, James BD, Stutzmann GE, Bennett DA, Miller SA, Rigo F, Marr RA, Hastings ML. Hinrich AJ, et al. Among authors: hastings ml. EMBO Mol Med. 2016 Apr 1;8(4):328-45. doi: 10.15252/emmm.201505846. EMBO Mol Med. 2016. PMID: 26902204 Free PMC article.

4

Determinants of exon 7 splicing in the spinal muscular atrophy genes, SMN1 and SMN2.

Cartegni L, Hastings ML, Calarco JA, de Stanchina E, Krainer AR. Cartegni L, et al. Among authors: hastings ml. Am J Hum Genet. 2006 Jan;78(1):63-77. doi: 10.1086/498853. Epub 2005 Nov 16. Am J Hum Genet. 2006. PMID: 16385450 Free PMC article.

5

Rescue of peripheral vestibular function in Usher syndrome mice using a splice-switching antisense oligonucleotide.

Vijayakumar S, Depreux FF, Jodelka FM, Lentz JJ, Rigo F, Jones TA, Hastings ML. Vijayakumar S, et al. Among authors: hastings ml. Hum Mol Genet. 2017 Sep 15;26(18):3482-3494. doi: 10.1093/hmg/ddx234. Hum Mol Genet. 2017. PMID: 28633508 Free PMC article.

6

Targeting SR proteins improves SMN expression in spinal muscular atrophy cells.

Wee CD, Havens MA, Jodelka FM, Hastings ML. Wee CD, et al. Among authors: hastings ml. PLoS One. 2014 Dec 15;9(12):e115205. doi: 10.1371/journal.pone.0115205. eCollection 2014. PLoS One. 2014. PMID: 25506695 Free PMC article.

7

Corticosteroid sensitization drives opioid addiction.

Carmack SA, Vendruscolo JCM, Adrienne McGinn M, Miranda-Barrientos J, Repunte-Canonigo V, Bosse GD, Mercatelli D, Giorgi FM, Fu Y, Hinrich AJ, Jodelka FM, Ling K, Messing RO, Peterson RT, Rigo F, Edwards S, Sanna PP, Morales M, Hastings ML, Koob GF, Vendruscolo LF. Carmack SA, et al. Among authors: hastings ml. Mol Psychiatry. 2022 May;27(5):2492-2501. doi: 10.1038/s41380-022-01501-1. Epub 2022 Mar 16. Mol Psychiatry. 2022. PMID: 35296810 Free PMC article.

8

Tetracyclines that promote SMN2 exon 7 splicing as therapeutics for spinal muscular atrophy.

Hastings ML, Berniac J, Liu YH, Abato P, Jodelka FM, Barthel L, Kumar S, Dudley C, Nelson M, Larson K, Edmonds J, Bowser T, Draper M, Higgins P, Krainer AR. Hastings ML, et al. Sci Transl Med. 2009 Nov 4;1(5):5ra12. doi: 10.1126/scitranslmed.3000208. Sci Transl Med. 2009. PMID: 20161659 Free PMC article.

9

Neurite Collapse and Altered ER Ca²⁺ Control in Human Parkinson Disease Patient iPSC-Derived Neurons with LRRK2 G2019S Mutation.

Korecka JA, Talbot S, Osborn TM, de Leeuw SM, Levy SA, Ferrari EJ, Moskites A, Atkinson E, Jodelka FM, Hinrich AJ, Hastings ML, Woolf CJ, Hallett PJ, Isacson O. Korecka JA, et al. Among authors: hastings ml. Stem Cell Reports. 2019 Jan 8;12(1):29-41. doi: 10.1016/j.stemcr.2018.11.021. Epub 2018 Dec 27. Stem Cell Reports. 2019. PMID: 30595548 Free PMC article.

10

Therapeutic efficacy of antisense oligonucleotides in mouse models of CLN3 Batten disease.

Centa JL, Jodelka FM, Hinrich AJ, Johnson TB, Ochaba J, Jackson M, Duelli DM, Weimer JM, Rigo F, Hastings ML. Centa JL, et al. Among authors: hastings ml. Nat Med. 2020 Sep;26(9):1444-1451. doi: 10.1038/s41591-020-0986-1. Epub 2020 Jul 27. Nat Med. 2020. PMID: 32719489 Free PMC article.

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