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Discovery and multi-parametric optimization of a high-affinity antibody against interleukin-25 with neutralizing activity in a mouse model of skin inflammation.
Bone R, Fennell BJ, Tam A, Sheldon R, Nocka K, Varghese S, Chang CS, Hawerkamp HC, Yeow A, Saunders SP, Hams E, Walsh PT, Cunningham O, Fallon PG. Bone R, et al. Among authors: hawerkamp hc. Antib Ther. 2022 Sep 29;5(4):258-267. doi: 10.1093/abt/tbac022. eCollection 2022 Oct. Antib Ther. 2022. PMID: 36299415 Free PMC article.
von Willebrand factor links primary hemostasis to innate immunity.
Drakeford C, Aguila S, Roche F, Hokamp K, Fazavana J, Cervantes MP, Curtis AM, Hawerkamp HC, Dhami SPS, Charles-Messance H, Hackett EE, Chion A, Ward S, Ahmad A, Schoen I, Breen E, Keane J, Murphy R, Preston RJS, O'Sullivan JM, Sheedy FJ, Fallon P, O'Donnell JS. Drakeford C, et al. Among authors: hawerkamp hc. Nat Commun. 2022 Nov 3;13(1):6320. doi: 10.1038/s41467-022-33796-7. Nat Commun. 2022. PMID: 36329021 Free PMC article.
Characterisation of the pro-inflammatory cytokine signature in severe COVID-19.
Hawerkamp HC, Dyer AH, Patil ND, McElheron M, O'Dowd N, O'Doherty L, Mhaonaigh AU, George AM, O'Halloran AM, Reddy C, Kenny RA, Little MA, Martin-Loeches I, Bergin C, Kennelly SP, Donnelly SC, Bourke NM, Long A, Sui J, Doherty DG, Conlon N, Cheallaigh CN, Fallon PG. Hawerkamp HC, et al. Front Immunol. 2023 Mar 30;14:1170012. doi: 10.3389/fimmu.2023.1170012. eCollection 2023. Front Immunol. 2023. PMID: 37063871 Free PMC article.
Study protocol for the St James's Hospital, Tallaght University Hospital, Trinity College Dublin Allied Researchers' (STTAR) Bioresource for COVID-19.
O'Doherty L, Hendricken Phelan S, Wood N, O'Brien S, Sui J, Mangan C, Howley F, O'Regan S, Razif NAM, Conlan C, Argue R, Holohan S, Dyer A, Salleh F, Townsend L, Hughes G, Kerr C, Reidy D, Sanz A, Connolly E, Kelly A, Leacy E, Reddy C, Gargan S, Breen E, Hawerkamp H, Dunne J, Martin-Loeches I, McLaughlin AM, Long A, Shiels O, Fallon P, Hennessy M, Romero-Ortuno R, Bannan C, Prior AR, Rakovac A, McCormack W, McManus R, Donnelly S, Bergin C, Little M, Ní Cheallaigh C, Conlon N. O'Doherty L, et al. HRB Open Res. 2022 Mar 16;5:20. doi: 10.12688/hrbopenres.13498.1. eCollection 2022. HRB Open Res. 2022. PMID: 35615437 Free PMC article.
12 results