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Year Number of Results
2015 1
2016 4
2017 1
2018 1
2019 2
2020 2
2021 1
2022 2
2023 1
2024 0

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14 results

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Page 1
Therapeutic implications of activating noncanonical PIK3CA mutations in head and neck squamous cell carcinoma.
Jin N, Keam B, Cho J, Lee MJ, Kim HR, Torosyan H, Jura N, Ng PK, Mills GB, Li H, Zeng Y, Barbash Z, Tarcic G, Kang H, Bauman JE, Kim MO, VanLandingham NK, Swaney DL, Krogan NJ, Johnson DE, Grandis JR. Jin N, et al. Among authors: torosyan h. J Clin Invest. 2021 Nov 15;131(22):e150335. doi: 10.1172/JCI150335. J Clin Invest. 2021. PMID: 34779417 Free PMC article.
CNPY4 inhibits the Hedgehog pathway by modulating membrane sterol lipids.
Lo M, Sharir A, Paul MD, Torosyan H, Agnew C, Li A, Neben C, Marangoni P, Xu L, Raleigh DR, Jura N, Klein OD. Lo M, et al. Among authors: torosyan h. Nat Commun. 2022 May 3;13(1):2407. doi: 10.1038/s41467-022-30186-x. Nat Commun. 2022. PMID: 35504891 Free PMC article.
The activities of drug inactive ingredients on biological targets.
Pottel J, Armstrong D, Zou L, Fekete A, Huang XP, Torosyan H, Bednarczyk D, Whitebread S, Bhhatarai B, Liang G, Jin H, Ghaemi SN, Slocum S, Lukacs KV, Irwin JJ, Berg EL, Giacomini KM, Roth BL, Shoichet BK, Urban L. Pottel J, et al. Among authors: torosyan h. Science. 2020 Jul 24;369(6502):403-413. doi: 10.1126/science.aaz9906. Science. 2020. PMID: 32703874 Free PMC article.
An Aggregation Advisor for Ligand Discovery.
Irwin JJ, Duan D, Torosyan H, Doak AK, Ziebart KT, Sterling T, Tumanian G, Shoichet BK. Irwin JJ, et al. Among authors: torosyan h. J Med Chem. 2015 Sep 10;58(17):7076-87. doi: 10.1021/acs.jmedchem.5b01105. Epub 2015 Aug 28. J Med Chem. 2015. PMID: 26295373 Free PMC article.
Identification of Novel Smoothened Ligands Using Structure-Based Docking.
Lacroix C, Fish I, Torosyan H, Parathaman P, Irwin JJ, Shoichet BK, Angers S. Lacroix C, et al. Among authors: torosyan h. PLoS One. 2016 Aug 4;11(8):e0160365. doi: 10.1371/journal.pone.0160365. eCollection 2016. PLoS One. 2016. PMID: 27490099 Free PMC article.
Robust Sequence Determinants of α-Synuclein Toxicity in Yeast Implicate Membrane Binding.
Newberry RW, Arhar T, Costello J, Hartoularos GC, Maxwell AM, Naing ZZC, Pittman M, Reddy NR, Schwarz DMC, Wassarman DR, Wu TS, Barrero D, Caggiano C, Catching A, Cavazos TB, Estes LS, Faust B, Fink EA, Goldman MA, Gomez YK, Gordon MG, Gunsalus LM, Hoppe N, Jaime-Garza M, Johnson MC, Jones MG, Kung AF, Lopez KE, Lumpe J, Martyn C, McCarthy EE, Miller-Vedam LE, Navarro EJ, Palar A, Pellegrino J, Saylor W, Stephens CA, Strickland J, Torosyan H, Wankowicz SA, Wong DR, Wong G, Redding S, Chow ED, DeGrado WF, Kampmann M. Newberry RW, et al. Among authors: torosyan h. ACS Chem Biol. 2020 Aug 21;15(8):2137-2153. doi: 10.1021/acschembio.0c00339. Epub 2020 Aug 12. ACS Chem Biol. 2020. PMID: 32786289 Free PMC article.
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