Hayashi N - Search Results

1

Mcl-1 and Bcl-xL cooperatively maintain integrity of hepatocytes in developing and adult murine liver.

Hikita H, Takehara T, Shimizu S, Kodama T, Li W, Miyagi T, Hosui A, Ishida H, Ohkawa K, Kanto T, Hiramatsu N, Yin XM, Hennighausen L, Tatsumi T, Hayashi N. Hikita H, et al. Among authors: hayashi n. Hepatology. 2009 Oct;50(4):1217-26. doi: 10.1002/hep.23126. Hepatology. 2009. PMID: 19676108 Free PMC article.

2

Hepatocyte-specific disruption of Bcl-xL leads to continuous hepatocyte apoptosis and liver fibrotic responses.

Takehara T, Tatsumi T, Suzuki T, Rucker EB 3rd, Hennighausen L, Jinushi M, Miyagi T, Kanazawa Y, Hayashi N. Takehara T, et al. Among authors: hayashi n. Gastroenterology. 2004 Oct;127(4):1189-97. doi: 10.1053/j.gastro.2004.07.019. Gastroenterology. 2004. PMID: 15480996

3

Concanavalin a injection activates intrahepatic innate immune cells to provoke an antitumor effect in murine liver.

Miyagi T, Takehara T, Tatsumi T, Suzuki T, Jinushi M, Kanazawa Y, Hiramatsu N, Kanto T, Tsuji S, Hori M, Hayashi N. Miyagi T, et al. Among authors: hayashi n. Hepatology. 2004 Nov;40(5):1190-6. doi: 10.1002/hep.20447. Hepatology. 2004. PMID: 15486936

4

Intrahepatic delivery of alpha-galactosylceramide-pulsed dendritic cells suppresses liver tumor.

Tatsumi T, Takehara T, Yamaguchi S, Sasakawa A, Sakamori R, Ohkawa K, Kohga K, Uemura A, Hayashi N. Tatsumi T, et al. Among authors: hayashi n. Hepatology. 2007 Jan;45(1):22-30. doi: 10.1002/hep.21447. Hepatology. 2007. PMID: 17187419

5

Signal transducer and activator of transcription 3 signaling within hepatocytes attenuates systemic inflammatory response and lethality in septic mice.

Sakamori R, Takehara T, Ohnishi C, Tatsumi T, Ohkawa K, Takeda K, Akira S, Hayashi N. Sakamori R, et al. Among authors: hayashi n. Hepatology. 2007 Nov;46(5):1564-73. doi: 10.1002/hep.21837. Hepatology. 2007. PMID: 17705264

6

BH3-only protein bid participates in the Bcl-2 network in healthy liver cells.

Hikita H, Takehara T, Kodama T, Shimizu S, Hosui A, Miyagi T, Tatsumi T, Ishida H, Ohkawa K, Li W, Kanto T, Hiramatsu N, Hennighausen L, Yin XM, Hayashi N. Hikita H, et al. Among authors: hayashi n. Hepatology. 2009 Dec;50(6):1972-80. doi: 10.1002/hep.23207. Hepatology. 2009. PMID: 19839062 Free PMC article.

7

Sorafenib inhibits the shedding of major histocompatibility complex class I-related chain A on hepatocellular carcinoma cells by down-regulating a disintegrin and metalloproteinase 9.

Kohga K, Takehara T, Tatsumi T, Ishida H, Miyagi T, Hosui A, Hayashi N. Kohga K, et al. Among authors: hayashi n. Hepatology. 2010 Apr;51(4):1264-73. doi: 10.1002/hep.23456. Hepatology. 2010. PMID: 20099300

8

The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma.

Shimizu S, Takehara T, Hikita H, Kodama T, Miyagi T, Hosui A, Tatsumi T, Ishida H, Noda T, Nagano H, Doki Y, Mori M, Hayashi N. Shimizu S, et al. Among authors: hayashi n. J Hepatol. 2010 May;52(5):698-704. doi: 10.1016/j.jhep.2009.12.024. Epub 2010 Mar 4. J Hepatol. 2010. PMID: 20347499

9

The Bcl-xL inhibitor, ABT-737, efficiently induces apoptosis and suppresses growth of hepatoma cells in combination with sorafenib.

Hikita H, Takehara T, Shimizu S, Kodama T, Shigekawa M, Iwase K, Hosui A, Miyagi T, Tatsumi T, Ishida H, Li W, Kanto T, Hiramatsu N, Hayashi N. Hikita H, et al. Among authors: hayashi n. Hepatology. 2010 Oct;52(4):1310-21. doi: 10.1002/hep.23836. Hepatology. 2010. PMID: 20799354

10

BH3-only activator proteins Bid and Bim are dispensable for Bak/Bax-dependent thrombocyte apoptosis induced by Bcl-xL deficiency: molecular requisites for the mitochondrial pathway to apoptosis in platelets.

Kodama T, Takehara T, Hikita H, Shimizu S, Shigekawa M, Li W, Miyagi T, Hosui A, Tatsumi T, Ishida H, Kanto T, Hiramatsu N, Yin XM, Hayashi N. Kodama T, et al. Among authors: hayashi n. J Biol Chem. 2011 Apr 22;286(16):13905-13. doi: 10.1074/jbc.M110.195370. Epub 2011 Mar 2. J Biol Chem. 2011. PMID: 21367852 Free PMC article.

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