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A novel apoA-I mutation (L178P) leads to endothelial dysfunction, increased arterial wall thickness, and premature coronary artery disease.
Hovingh GK, Brownlie A, Bisoendial RJ, Dube MP, Levels JH, Petersen W, Dullaart RP, Stroes ES, Zwinderman AH, de Groot E, Hayden MR, Kuivenhoven JA, Kastelein JJ. Hovingh GK, et al. Among authors: hayden mr. J Am Coll Cardiol. 2004 Oct 6;44(7):1429-35. doi: 10.1016/j.jacc.2004.06.070. J Am Coll Cardiol. 2004. PMID: 15464323 Free article.
ABCA8 Regulates Cholesterol Efflux and High-Density Lipoprotein Cholesterol Levels.
Trigueros-Motos L, van Capelleveen JC, Torta F, Castaño D, Zhang LH, Chai EC, Kang M, Dimova LG, Schimmel AWM, Tietjen I, Radomski C, Tan LJ, Thiam CH, Narayanaswamy P, Wu DH, Dorninger F, Yakala GK, Barhdadi A, Angeli V, Dubé MP, Berger J, Dallinga-Thie GM, Tietge UJF, Wenk MR, Hayden MR, Hovingh GK, Singaraja RR. Trigueros-Motos L, et al. Among authors: hayden mr. Arterioscler Thromb Vasc Biol. 2017 Nov;37(11):2147-2155. doi: 10.1161/ATVBAHA.117.309574. Epub 2017 Sep 7. Arterioscler Thromb Vasc Biol. 2017. PMID: 28882873
Increased ABCA1 activity protects against atherosclerosis.
Singaraja RR, Fievet C, Castro G, James ER, Hennuyer N, Clee SM, Bissada N, Choy JC, Fruchart JC, McManus BM, Staels B, Hayden MR. Singaraja RR, et al. Among authors: hayden mr. J Clin Invest. 2002 Jul;110(1):35-42. doi: 10.1172/JCI15748. J Clin Invest. 2002. PMID: 12093886 Free PMC article.
Identification and functional analysis of a naturally occurring E89K mutation in the ABCA1 gene of the WHAM chicken.
Attie AD, Hamon Y, Brooks-Wilson AR, Gray-Keller MP, MacDonald ML, Rigot V, Tebon A, Zhang LH, Mulligan JD, Singaraja RR, Bitgood JJ, Cook ME, Kastelein JJ, Chimini G, Hayden MR. Attie AD, et al. Among authors: hayden mr. J Lipid Res. 2002 Oct;43(10):1610-7. doi: 10.1194/jlr.m200223-jlr200. J Lipid Res. 2002. PMID: 12364545 Free article.
891 results