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The NADPH oxidase NOX2 is a marker of adverse prognosis involved in chemoresistance of acute myeloid leukemias.
Paolillo R, Boulanger M, Gâtel P, Gabellier L, De Toledo M, Tempé D, Hallal R, Akl D, Moreaux J, Baik H, Gueret E, Recher C, Sarry JE, Cartron G, Piechaczyk M, Bossis G. Paolillo R, et al. Among authors: baik h. Haematologica. 2022 Nov 1;107(11):2562-2575. doi: 10.3324/haematol.2021.279889. Haematologica. 2022. PMID: 35172562 Free PMC article.
Chemical Synthesis of TFF3 Reveals Novel Mechanistic Insights and a Gut-Stable Metabolite.
Braga Emidio N, Meli R, Tran HNT, Baik H, Morisset-Lopez S, Elliott AG, Blaskovich MAT, Spiller S, Beck-Sickinger AG, Schroeder CI, Muttenthaler M. Braga Emidio N, et al. Among authors: baik h. J Med Chem. 2021 Jul 8;64(13):9484-9495. doi: 10.1021/acs.jmedchem.1c00767. Epub 2021 Jun 18. J Med Chem. 2021. PMID: 34142550 Free PMC article.
Recurrent MLK4 Loss-of-Function Mutations Suppress JNK Signaling to Promote Colon Tumorigenesis.
Marusiak AA, Stephenson NL, Baik H, Trotter EW, Li Y, Blyth K, Mason S, Chapman P, Puto LA, Read JA, Brassington C, Pollard HK, Phillips C, Green I, Overman R, Collier M, Testoni E, Miller CJ, Hunter T, Sansom OJ, Brognard J. Marusiak AA, et al. Among authors: baik h. Cancer Res. 2016 Feb 1;76(3):724-35. doi: 10.1158/0008-5472.CAN-15-0701-T. Epub 2015 Dec 4. Cancer Res. 2016. PMID: 26637668 Free PMC article.
Chemical synthesis of human trefoil factor 1 (TFF1) and its homodimer provides novel insights into their mechanisms of action.
Braga Emidio N , Baik H , Lee D , Stürmer R , Heuer J , Elliott AG , Blaskovich MAT , Haupenthal K , Tegtmeyer N , Hoffmann W , Schroeder CI , Muttenthaler M . Braga Emidio N , et al. Among authors: baik h. Chem Commun (Camb). 2020 Jun 14;56(47):6420-6423. doi: 10.1039/d0cc02321c. Epub 2020 May 11. Chem Commun (Camb). 2020. PMID: 32391824 Free PMC article.