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Page 1
Defining the condensate landscape of fusion oncoproteins.
Tripathi S, Shirnekhi HK, Gorman SD, Chandra B, Baggett DW, Park CG, Somjee R, Lang B, Hosseini SMH, Pioso BJ, Li Y, Iacobucci I, Gao Q, Edmonson MN, Rice SV, Zhou X, Bollinger J, Mitrea DM, White MR, McGrail DJ, Jarosz DF, Yi SS, Babu MM, Mullighan CG, Zhang J, Sahni N, Kriwacki RW. Tripathi S, et al. Among authors: shirnekhi hk. Nat Commun. 2023 Sep 28;14(1):6008. doi: 10.1038/s41467-023-41655-2. Nat Commun. 2023. PMID: 37770423 Free PMC article.
Phase Separation Mediates NUP98 Fusion Oncoprotein Leukemic Transformation.
Chandra B, Michmerhuizen NL, Shirnekhi HK, Tripathi S, Pioso BJ, Baggett DW, Mitrea DM, Iacobucci I, White MR, Chen J, Park CG, Wu H, Pounds S, Medyukhina A, Khairy K, Gao Q, Qu C, Abdelhamed S, Gorman SD, Bawa S, Maslanka C, Kinger S, Dogra P, Ferrolino MC, Di Giacomo D, Mecucci C, Klco JM, Mullighan CG, Kriwacki RW. Chandra B, et al. Among authors: shirnekhi hk. Cancer Discov. 2022 Apr 1;12(4):1152-1169. doi: 10.1158/2159-8290.CD-21-0674. Cancer Discov. 2022. PMID: 34903620 Free PMC article.
Hyper-active RAS/MAPK introduces cancer-specific mitotic vulnerabilities.
Herman JA, Romain RR, Hoellerbauer P, Shirnekhi HK, King DC, DeLuca KF, Osborne Nishimura E, Paddison PJ, DeLuca JG. Herman JA, et al. Among authors: shirnekhi hk. Proc Natl Acad Sci U S A. 2022 Oct 11;119(41):e2208255119. doi: 10.1073/pnas.2208255119. Epub 2022 Oct 3. Proc Natl Acad Sci U S A. 2022. PMID: 36191188 Free PMC article.