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Discovery of LSZ102, a Potent, Orally Bioavailable Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen Receptor Positive Breast Cancer.
Tria GS, Abrams T, Baird J, Burks HE, Firestone B, Gaither LA, Hamann LG, He G, Kirby CA, Kim S, Lombardo F, Macchi KJ, McDonnell DP, Mishina Y, Norris JD, Nunez J, Springer C, Sun Y, Thomsen NM, Wang C, Wang J, Yu B, Tiong-Yip CL, Peukert S. Tria GS, et al. Among authors: he g. J Med Chem. 2018 Apr 12;61(7):2837-2864. doi: 10.1021/acs.jmedchem.7b01682. Epub 2018 Mar 22. J Med Chem. 2018. PMID: 29562737
Discovery of 2-Pyridylpyrimidines as the First Orally Bioavailable GPR39 Agonists.
Peukert S, Hughes R, Nunez J, He G, Yan Z, Jain R, Llamas L, Luchansky S, Carlson A, Liang G, Kunjathoor V, Pietropaolo M, Shapiro J, Castellana A, Wu X, Bose A. Peukert S, et al. Among authors: he g. ACS Med Chem Lett. 2014 Aug 4;5(10):1114-8. doi: 10.1021/ml500240d. eCollection 2014 Oct 9. ACS Med Chem Lett. 2014. PMID: 25313322 Free PMC article.
4-(Pyrazol-4-yl)-pyrimidines as selective inhibitors of cyclin-dependent kinase 4/6.
Cho YS, Borland M, Brain C, Chen CH, Cheng H, Chopra R, Chung K, Groarke J, He G, Hou Y, Kim S, Kovats S, Lu Y, O'Reilly M, Shen J, Smith T, Trakshel G, Vögtle M, Xu M, Xu M, Sung MJ. Cho YS, et al. Among authors: he g. J Med Chem. 2010 Nov 25;53(22):7938-57. doi: 10.1021/jm100571n. Epub 2010 Nov 1. J Med Chem. 2010. PMID: 21038853
Corrigendum to "Genome sequencing of Porostereum spadiceum to study the degradation of levofloxacin" [Ecotoxicol. Environ. Saf. 270 (2024) 115808].
Ben Ayed A, Akrout I, Staita K, Albert Q, Greff S, Simmler C, Ahrendt S, LaButti K, Lipzen A, He G, Savage E, Armengaud J, Kielbasa M, Navarro D, Drula E, Turbé-Doan A, Bertrand E, Lomascolo A, Chaduli D, Faulds CB, Chamkha M, Maalej A, Barry K, Grigoriev IV, Martin F, Zouari-Mechichi H, Sciara G, Mechichi T, Record E. Ben Ayed A, et al. Among authors: he g. Ecotoxicol Environ Saf. 2024 Apr 30;278:116408. doi: 10.1016/j.ecoenv.2024.116408. Online ahead of print. Ecotoxicol Environ Saf. 2024. PMID: 38691880 No abstract available.
Integrating network pharmacology and experimental validation reveals therapeutic effects of D-mannose on NAFLD through mTOR suppression.
Zhang S, Gao YF, Zhang K, Deng GR, He GX, Gao PP, Yu YK, Yuan Y, Xing SJ, Zhao N, Zhang H, Di-Wu YC, Liu YH, Sui BD, Li Z, Ma J, Zheng CX. Zhang S, et al. Among authors: he gx. Biochem Biophys Res Commun. 2024 Apr 24;715:149999. doi: 10.1016/j.bbrc.2024.149999. Online ahead of print. Biochem Biophys Res Commun. 2024. PMID: 38678787
5,993 results