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Individual red blood cell fetal hemoglobin quantification allows to determine protective thresholds in sickle cell disease.
Hebert N, Rakotoson MG, Bodivit G, Audureau E, Bencheikh L, Kiger L, Oubaya N, Pakdaman S, Sakka M, Di Liberto G, Chadebech P, Vingert B, Pirenne F, Galactéros F, Cambot M, Bartolucci P. Hebert N, et al. Am J Hematol. 2020 Nov;95(11):1235-1245. doi: 10.1002/ajh.25937. Epub 2020 Aug 25. Am J Hematol. 2020. PMID: 32681733 Free article. Clinical Trial.
Red blood cell generation from human induced pluripotent stem cells: perspectives for transfusion medicine.
Lapillonne H, Kobari L, Mazurier C, Tropel P, Giarratana MC, Zanella-Cleon I, Kiger L, Wattenhofer-Donzé M, Puccio H, Hebert N, Francina A, Andreu G, Viville S, Douay L. Lapillonne H, et al. Among authors: hebert n. Haematologica. 2010 Oct;95(10):1651-9. doi: 10.3324/haematol.2010.023556. Epub 2010 May 21. Haematologica. 2010. PMID: 20494935 Free PMC article.
Proof of principle for transfusion of in vitro-generated red blood cells.
Giarratana MC, Rouard H, Dumont A, Kiger L, Safeukui I, Le Pennec PY, François S, Trugnan G, Peyrard T, Marie T, Jolly S, Hebert N, Mazurier C, Mario N, Harmand L, Lapillonne H, Devaux JY, Douay L. Giarratana MC, et al. Among authors: hebert n. Blood. 2011 Nov 10;118(19):5071-9. doi: 10.1182/blood-2011-06-362038. Epub 2011 Sep 1. Blood. 2011. PMID: 21885599 Free PMC article. Clinical Trial.
Human induced pluripotent stem cells can reach complete terminal maturation: in vivo and in vitro evidence in the erythropoietic differentiation model.
Kobari L, Yates F, Oudrhiri N, Francina A, Kiger L, Mazurier C, Rouzbeh S, El-Nemer W, Hebert N, Giarratana MC, François S, Chapel A, Lapillonne H, Luton D, Bennaceur-Griscelli A, Douay L. Kobari L, et al. Among authors: hebert n. Haematologica. 2012 Dec;97(12):1795-803. doi: 10.3324/haematol.2011.055566. Epub 2012 Jun 24. Haematologica. 2012. PMID: 22733021 Free PMC article.
Long-term outcomes of lentiviral gene therapy for the β-hemoglobinopathies: the HGB-205 trial.
Magrin E, Semeraro M, Hebert N, Joseph L, Magnani A, Chalumeau A, Gabrion A, Roudaut C, Marouene J, Lefrere F, Diana JS, Denis A, Neven B, Funck-Brentano I, Negre O, Renolleau S, Brousse V, Kiger L, Touzot F, Poirot C, Bourget P, El Nemer W, Blanche S, Tréluyer JM, Asmal M, Walls C, Beuzard Y, Schmidt M, Hacein-Bey-Abina S, Asnafi V, Guichard I, Poirée M, Monpoux F, Touraine P, Brouzes C, de Montalembert M, Payen E, Six E, Ribeil JA, Miccio A, Bartolucci P, Leboulch P, Cavazzana M. Magrin E, et al. Among authors: hebert n. Nat Med. 2022 Jan;28(1):81-88. doi: 10.1038/s41591-021-01650-w. Epub 2022 Jan 24. Nat Med. 2022. PMID: 35075288 Clinical Trial.
Preclinical evaluation of the preservation of red blood cell concentrates by hypoxic storage technology for transfusion in sickle cell disease.
Bencheikh L, Nguyen KA, Chadebech P, Kiger L, Bodivit G, Jouard A, Pakdaman S, Adypagavane S, Audureau E, Tebbakha K, Bocquet T, Mignen B, Hebert N, Seguin M, Pirenne F, Sowemimo-Coker S, Dunham A, Bartolucci P. Bencheikh L, et al. Among authors: hebert n. Haematologica. 2022 Aug 1;107(8):1944-1949. doi: 10.3324/haematol.2021.279721. Haematologica. 2022. PMID: 35354249 Free PMC article. No abstract available.
Genetic reversal of the globin switch concurrently modulates both fetal and sickle hemoglobin and reduces red cell sickling.
De Souza DC, Hebert N, Esrick EB, Ciuculescu MF, Archer NM, Armant M, Audureau É, Brendel C, Di Caprio G, Galactéros F, Liu D, McCabe A, Morris E, Schonbrun E, Williams D, Wood DK, Williams DA, Bartolucci P, Higgins JM. De Souza DC, et al. Among authors: hebert n. Nat Commun. 2023 Sep 20;14(1):5850. doi: 10.1038/s41467-023-40923-5. Nat Commun. 2023. PMID: 37730674 Free PMC article.
60 results