Heighway J - Search Results

1

Maspin - the most commonly-expressed gene of the 18q21.3 serpin cluster in lung cancer - is strongly expressed in preneoplastic bronchial lesions.

Smith SL, Watson SG, Ratschiller D, Gugger M, Betticher DC, Heighway J. Smith SL, et al. Among authors: heighway j. Oncogene. 2003 Nov 27;22(54):8677-87. doi: 10.1038/sj.onc.1207127. Oncogene. 2003. PMID: 14647462

2

Expression profiling of primary non-small cell lung cancer for target identification.

Heighway J, Knapp T, Boyce L, Brennand S, Field JK, Betticher DC, Ratschiller D, Gugger M, Donovan M, Lasek A, Rickert P. Heighway J, et al. Oncogene. 2002 Oct 31;21(50):7749-63. doi: 10.1038/sj.onc.1205979. Oncogene. 2002. PMID: 12400018

3

S100A2 is strongly expressed in airway basal cells, preneoplastic bronchial lesions and primary non-small cell lung carcinomas.

Smith SL, Gugger M, Hoban P, Ratschiller D, Watson SG, Field JK, Betticher DC, Heighway J. Smith SL, et al. Among authors: heighway j. Br J Cancer. 2004 Oct 18;91(8):1515-24. doi: 10.1038/sj.bjc.6602188. Br J Cancer. 2004. PMID: 15467767 Free PMC article.

4

Overexpression of aurora B kinase (AURKB) in primary non-small cell lung carcinoma is frequent, generally driven from one allele, and correlates with the level of genetic instability.

Smith SL, Bowers NL, Betticher DC, Gautschi O, Ratschiller D, Hoban PR, Booton R, Santibáñez-Koref MF, Heighway J. Smith SL, et al. Among authors: heighway j. Br J Cancer. 2005 Sep 19;93(6):719-29. doi: 10.1038/sj.bjc.6602779. Br J Cancer. 2005. PMID: 16222316 Free PMC article.

5

Comparative multiplex PCR and allele-specific expression analysis in human lung cancer. Tools to facilitate target identification.

Heighway J, Betticher D, Knapp T, Hoban P. Heighway J, et al. Methods Mol Med. 2003;75:291-304. doi: 10.1385/1-59259-324-0:291. Methods Mol Med. 2003. PMID: 12407748 No abstract available.

6

Alternate splicing produces a novel cyclin D1 transcript.

Betticher DC, Thatcher N, Altermatt HJ, Hoban P, Ryder WD, Heighway J. Betticher DC, et al. Among authors: heighway j. Oncogene. 1995 Sep 7;11(5):1005-11. Oncogene. 1995. PMID: 7675441

7

The use of allelic expression differences to ascertain functional polymorphisms acting in cis: analysis of MMP1 transcripts in normal lung tissue.

Heighway J, Bowers NL, Smith S, Betticher DC, Koref MF. Heighway J, et al. Ann Hum Genet. 2005 Jan;69(Pt 1):127-33. doi: 10.1046/j.1529-8817.2004.00135.x. Ann Hum Genet. 2005. PMID: 15638833

8

Cyclin D1 (CCND1) A870G gene polymorphism modulates smoking-induced lung cancer risk and response to platinum-based chemotherapy in non-small cell lung cancer (NSCLC) patients.

Gautschi O, Hugli B, Ziegler A, Bigosch C, Bowers NL, Ratschiller D, Jermann M, Stahel RA, Heighway J, Betticher DC. Gautschi O, et al. Among authors: heighway j. Lung Cancer. 2006 Mar;51(3):303-11. doi: 10.1016/j.lungcan.2005.10.025. Epub 2006 Jan 10. Lung Cancer. 2006. PMID: 16406195

9

Cyclin D1 in non-small cell lung cancer: a key driver of malignant transformation.

Gautschi O, Ratschiller D, Gugger M, Betticher DC, Heighway J. Gautschi O, et al. Among authors: heighway j. Lung Cancer. 2007 Jan;55(1):1-14. doi: 10.1016/j.lungcan.2006.09.024. Epub 2006 Oct 27. Lung Cancer. 2007. PMID: 17070615 Review.

10

Expression of p16INK4a/p16alpha and p19ARF/p16beta is frequently altered in non-small cell lung cancer and correlates with p53 overexpression.

Vonlanthen S, Heighway J, Tschan MP, Borner MM, Altermatt HJ, Kappeler A, Tobler A, Fey MF, Thatcher N, Yarbrough WG, Betticher DC. Vonlanthen S, et al. Among authors: heighway j. Oncogene. 1998 Nov 26;17(21):2779-85. doi: 10.1038/sj.onc.1202501. Oncogene. 1998. PMID: 9840942

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