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Derivation of Human Midbrain-Specific Organoids from Neuroepithelial Stem Cells.
Monzel AS, Smits LM, Hemmer K, Hachi S, Moreno EL, van Wuellen T, Jarazo J, Walter J, Brüggemann I, Boussaad I, Berger E, Fleming RMT, Bolognin S, Schwamborn JC. Monzel AS, et al. Among authors: hemmer k. Stem Cell Reports. 2017 May 9;8(5):1144-1154. doi: 10.1016/j.stemcr.2017.03.010. Epub 2017 Apr 13. Stem Cell Reports. 2017. PMID: 28416282 Free PMC article.
Machine learning-assisted neurotoxicity prediction in human midbrain organoids.
Monzel AS, Hemmer K, Kaoma T, Smits LM, Bolognin S, Lucarelli P, Rosety I, Zagare A, Antony P, Nickels SL, Krueger R, Azuaje F, Schwamborn JC. Monzel AS, et al. Among authors: hemmer k. Parkinsonism Relat Disord. 2020 Jun;75:105-109. doi: 10.1016/j.parkreldis.2020.05.011. Epub 2020 May 8. Parkinsonism Relat Disord. 2020. PMID: 32534431 Free article.
Origin-dependent neural cell identities in differentiated human iPSCs in vitro and after transplantation into the mouse brain.
Hargus G, Ehrlich M, Araúzo-Bravo MJ, Hemmer K, Hallmann AL, Reinhardt P, Kim KP, Adachi K, Santourlidis S, Ghanjati F, Fauser M, Ossig C, Storch A, Kim JB, Schwamborn JC, Sterneckert J, Schöler HR, Kuhlmann T, Zaehres H. Hargus G, et al. Among authors: hemmer k. Cell Rep. 2014 Sep 25;8(6):1697-1703. doi: 10.1016/j.celrep.2014.08.014. Epub 2014 Sep 15. Cell Rep. 2014. PMID: 25220454 Free article.
Modeling Parkinson's disease in midbrain-like organoids.
Smits LM, Reinhardt L, Reinhardt P, Glatza M, Monzel AS, Stanslowsky N, Rosato-Siri MD, Zanon A, Antony PM, Bellmann J, Nicklas SM, Hemmer K, Qing X, Berger E, Kalmbach N, Ehrlich M, Bolognin S, Hicks AA, Wegner F, Sterneckert JL, Schwamborn JC. Smits LM, et al. Among authors: hemmer k. NPJ Parkinsons Dis. 2019 Apr 5;5:5. doi: 10.1038/s41531-019-0078-4. eCollection 2019. NPJ Parkinsons Dis. 2019. PMID: 30963107 Free PMC article.
Impaired serine metabolism complements LRRK2-G2019S pathogenicity in PD patients.
Nickels SL, Walter J, Bolognin S, Gérard D, Jaeger C, Qing X, Tisserand J, Jarazo J, Hemmer K, Harms A, Halder R, Lucarelli P, Berger E, Antony PMA, Glaab E, Hankemeier T, Klein C, Sauter T, Sinkkonen L, Schwamborn JC. Nickels SL, et al. Among authors: hemmer k. Parkinsonism Relat Disord. 2019 Oct;67:48-55. doi: 10.1016/j.parkreldis.2019.09.018. Epub 2019 Sep 19. Parkinsonism Relat Disord. 2019. PMID: 31621607 Free article.
Direct reprogramming of fibroblasts into neural stem cells by defined factors.
Han DW, Tapia N, Hermann A, Hemmer K, Höing S, Araúzo-Bravo MJ, Zaehres H, Wu G, Frank S, Moritz S, Greber B, Yang JH, Lee HT, Schwamborn JC, Storch A, Schöler HR. Han DW, et al. Among authors: hemmer k. Cell Stem Cell. 2012 Apr 6;10(4):465-72. doi: 10.1016/j.stem.2012.02.021. Epub 2012 Mar 22. Cell Stem Cell. 2012. PMID: 22445517 Free article.
Derivation and expansion using only small molecules of human neural progenitors for neurodegenerative disease modeling.
Reinhardt P, Glatza M, Hemmer K, Tsytsyura Y, Thiel CS, Höing S, Moritz S, Parga JA, Wagner L, Bruder JM, Wu G, Schmid B, Röpke A, Klingauf J, Schwamborn JC, Gasser T, Schöler HR, Sterneckert J. Reinhardt P, et al. Among authors: hemmer k. PLoS One. 2013;8(3):e59252. doi: 10.1371/journal.pone.0059252. Epub 2013 Mar 22. PLoS One. 2013. PMID: 23533608 Free PMC article.
31 results