Hemmings BA - Search Results

1

PKB/AKT phosphorylation of the transcription factor Twist-1 at Ser42 inhibits p53 activity in response to DNA damage.

Vichalkovski A, Gresko E, Hess D, Restuccia DF, Hemmings BA. Vichalkovski A, et al. Among authors: hemmings ba. Oncogene. 2010 Jun 17;29(24):3554-65. doi: 10.1038/onc.2010.115. Epub 2010 Apr 19. Oncogene. 2010. PMID: 20400976

2

Akt/PKB-mediated phosphorylation of Twist1 promotes tumor metastasis via mediating cross-talk between PI3K/Akt and TGF-β signaling axes.

Xue G, Restuccia DF, Lan Q, Hynx D, Dirnhofer S, Hess D, Rüegg C, Hemmings BA. Xue G, et al. Among authors: hemmings ba. Cancer Discov. 2012 Mar;2(3):248-59. doi: 10.1158/2159-8290.CD-11-0270. Epub 2012 Jan 25. Cancer Discov. 2012. PMID: 22585995

3

PI3K-PKB/Akt pathway.

Hemmings BA, Restuccia DF. Hemmings BA, et al. Cold Spring Harb Perspect Biol. 2012 Sep 1;4(9):a011189. doi: 10.1101/cshperspect.a011189. Cold Spring Harb Perspect Biol. 2012. PMID: 22952397 Free PMC article. Review.

4

PML tumor suppressor is regulated by HIPK2-mediated phosphorylation in response to DNA damage.

Gresko E, Ritterhoff S, Sevilla-Perez J, Roscic A, Fröbius K, Kotevic I, Vichalkovski A, Hess D, Hemmings BA, Schmitz ML. Gresko E, et al. Among authors: hemmings ba. Oncogene. 2009 Feb 5;28(5):698-708. doi: 10.1038/onc.2008.420. Epub 2008 Nov 17. Oncogene. 2009. PMID: 19015637

5

Cell signaling. Blocking Akt-ivity.

Restuccia DF, Hemmings BA. Restuccia DF, et al. Among authors: hemmings ba. Science. 2009 Aug 28;325(5944):1083-4. doi: 10.1126/science.1179972. Science. 2009. PMID: 19713516 No abstract available.

6

Stabilization of Mdm2 via decreased ubiquitination is mediated by protein kinase B/Akt-dependent phosphorylation.

Feng J, Tamaskovic R, Yang Z, Brazil DP, Merlo A, Hess D, Hemmings BA. Feng J, et al. Among authors: hemmings ba. J Biol Chem. 2004 Aug 20;279(34):35510-7. doi: 10.1074/jbc.M404936200. Epub 2004 May 28. J Biol Chem. 2004. PMID: 15169778 Free article.

7

Identification of a PKB/Akt hydrophobic motif Ser-473 kinase as DNA-dependent protein kinase.

Feng J, Park J, Cron P, Hess D, Hemmings BA. Feng J, et al. Among authors: hemmings ba. J Biol Chem. 2004 Sep 24;279(39):41189-96. doi: 10.1074/jbc.M406731200. Epub 2004 Jul 15. J Biol Chem. 2004. PMID: 15262962 Free article.

8

NDR kinase is activated by RASSF1A/MST1 in response to Fas receptor stimulation and promotes apoptosis.

Vichalkovski A, Gresko E, Cornils H, Hergovich A, Schmitz D, Hemmings BA. Vichalkovski A, et al. Among authors: hemmings ba. Curr Biol. 2008 Dec 9;18(23):1889-95. doi: 10.1016/j.cub.2008.10.060. Curr Biol. 2008. PMID: 19062280 Free article.

9

Targeting the Kinome II.

Hemmings BA, Restuccia D, Tonks N. Hemmings BA, et al. Curr Opin Cell Biol. 2009 Apr;21(2):135-9. doi: 10.1016/j.ceb.2009.03.001. Epub 2009 Apr 1. Curr Opin Cell Biol. 2009. PMID: 19342212 No abstract available.

10

From man to mouse and back again: advances in defining tumor AKTivities in vivo.

Restuccia DF, Hemmings BA. Restuccia DF, et al. Among authors: hemmings ba. Dis Model Mech. 2010 Nov-Dec;3(11-12):705-20. doi: 10.1242/dmm.004671. Epub 2010 Oct 12. Dis Model Mech. 2010. PMID: 20940316 Free article. Review.

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