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VEGF-ablation therapy reduces drug delivery and therapeutic response in ECM-dense tumors.
Röhrig F, Vorlová S, Hoffmann H, Wartenberg M, Escorcia FE, Keller S, Tenspolde M, Weigand I, Gätzner S, Manova K, Penack O, Scheinberg DA, Rosenwald A, Ergün S, Granot Z, Henke E. Röhrig F, et al. Among authors: henke e. Oncogene. 2017 Jan 5;36(1):1-12. doi: 10.1038/onc.2016.182. Epub 2016 Jun 6. Oncogene. 2017. PMID: 27270432 Free PMC article.
LOX-catalyzed collagen stabilization is a proximal cause for intrinsic resistance to chemotherapy.
Rossow L, Veitl S, Vorlová S, Wax JK, Kuhn AE, Maltzahn V, Upcin B, Karl F, Hoffmann H, Gätzner S, Kallius M, Nandigama R, Scheld D, Irmak S, Herterich S, Zernecke A, Ergün S, Henke E. Rossow L, et al. Among authors: henke e. Oncogene. 2018 Sep;37(36):4921-4940. doi: 10.1038/s41388-018-0320-2. Epub 2018 May 21. Oncogene. 2018. PMID: 29780168 Free PMC article.
Restriction of drug transport by the tumor environment.
Nandigama R, Upcin B, Aktas BH, Ergün S, Henke E. Nandigama R, et al. Among authors: henke e. Histochem Cell Biol. 2018 Dec;150(6):631-648. doi: 10.1007/s00418-018-1744-z. Epub 2018 Oct 25. Histochem Cell Biol. 2018. PMID: 30361778 Review.
76 results