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A vaccine conjugate of 'ISCAR' immunocarrier and peptide epitopes of the E7 cervical cancer-associated protein of human papillomavirus type 16 elicits specific Th1- and Th2-type responses in immunized mice in the absence of oil-based adjuvants.
Tindle RW, Croft S, Herd K, Malcolm K, Geczy AF, Stewart T, Fernando GJ. Tindle RW, et al. Among authors: herd k. Clin Exp Immunol. 1995 Aug;101(2):265-71. doi: 10.1111/j.1365-2249.1995.tb08349.x. Clin Exp Immunol. 1995. PMID: 7544248 Free PMC article.
Human papillomavirus type 16 E7 oncoprotein expressed in peripheral epithelium tolerizes E7-directed cytotoxic T-lymphocyte precursors restricted through human (and mouse) major histocompatibility complex class I alleles.
Doan T, Herd K, Street M, Bryson G, Fernando G, Lambert P, Tindle R. Doan T, et al. Among authors: herd k. J Virol. 1999 Jul;73(7):6166-70. doi: 10.1128/JVI.73.7.6166-6170.1999. J Virol. 1999. PMID: 10364377 Free PMC article.
Mice which coexpress human papillomavirus type 16 E7 and HLA A2.1 in peripheral squamous epithelium and thymic cortical epithelium are tolerant at the cytotoxic T-lymphocyte (CTL) level to E7 epitopes restricted through HLA A*0201 and H-2(b) (T. Doan, M. Chambers, M. Street, G. J …
Mice which coexpress human papillomavirus type 16 E7 and HLA A2.1 in peripheral squamous epithelium and thymic cortical epithelium are toler …
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