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Pembrolizumab plus azacitidine in patients with chemotherapy refractory metastatic colorectal cancer: a single-arm phase 2 trial and correlative biomarker analysis.
Kuang C, Park Y, Augustin RC, Lin Y, Hartman DJ, Seigh L, Pai RK, Sun W, Bahary N, Ohr J, Rhee JC, Marks SM, Beasley HS, Shuai Y, Herman JG, Zarour HM, Chu E, Lee JJ, Krishnamurthy A. Kuang C, et al. Among authors: herman jg. Clin Epigenetics. 2022 Jan 6;14(1):3. doi: 10.1186/s13148-021-01226-y. Clin Epigenetics. 2022. PMID: 34991708 Free PMC article. Clinical Trial.
GPX3 promoter methylation predicts platinum sensitivity in colorectal cancer.
Pelosof L, Yerram S, Armstrong T, Chu N, Danilova L, Yanagisawa B, Hidalgo M, Azad N, Herman JG. Pelosof L, et al. Among authors: herman jg. Epigenetics. 2017 Jul 3;12(7):540-550. doi: 10.1080/15592294.2016.1265711. Epub 2016 Dec 5. Epigenetics. 2017. PMID: 27918237 Free PMC article.
A phase 2 trial of gemcitabine and docetaxel in patients with metastatic colorectal adenocarcinoma with methylated checkpoint with forkhead and ring finger domain promoter and/or microsatellite instability phenotype.
Baretti M, Karunasena E, Zahurak M, Walker R, Zhao Y, Pisanic TR 2nd, Wang TH, Greten TF, Duffy AG, Gootjes E, Meijer G, Verheul HMW, Ahuja N, Herman JG, Azad NS. Baretti M, et al. Among authors: herman jg. Clin Transl Sci. 2021 May;14(3):954-963. doi: 10.1111/cts.12960. Epub 2021 Apr 3. Clin Transl Sci. 2021. PMID: 33811727 Free PMC article. Clinical Trial.
Identification of DNA methylation markers for early detection of CRC indicates a role for nervous system-related genes in CRC.
Rademakers G, Massen M, Koch A, Draht MX, Buekers N, Wouters KAD, Vaes N, De Meyer T, Carvalho B, Meijer GA, Herman JG, Smits KM, van Engeland M, Melotte V. Rademakers G, et al. Among authors: herman jg. Clin Epigenetics. 2021 Apr 15;13(1):80. doi: 10.1186/s13148-021-01067-9. Clin Epigenetics. 2021. PMID: 33858496 Free PMC article.
383 results