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Experimental gene therapies for the NCLs.
Liu W, Kleine-Holthaus SM, Herranz-Martin S, Aristorena M, Mole SE, Smith AJ, Ali RR, Rahim AA. Liu W, et al. Among authors: herranz martin s. Biochim Biophys Acta Mol Basis Dis. 2020 Sep 1;1866(9):165772. doi: 10.1016/j.bbadis.2020.165772. Epub 2020 Mar 24. Biochim Biophys Acta Mol Basis Dis. 2020. PMID: 32220628 Free article. Review.
Future Prospects of Gene Therapy for Friedreich's Ataxia.
Ocana-Santero G, Díaz-Nido J, Herranz-Martín S. Ocana-Santero G, et al. Among authors: herranz martin s. Int J Mol Sci. 2021 Feb 11;22(4):1815. doi: 10.3390/ijms22041815. Int J Mol Sci. 2021. PMID: 33670433 Free PMC article. Review.
Current developments in gene therapy for amyotrophic lateral sclerosis.
Scarrott JM, Herranz-Martín S, Alrafiah AR, Shaw PJ, Azzouz M. Scarrott JM, et al. Among authors: herranz martin s. Expert Opin Biol Ther. 2015 Jul;15(7):935-47. doi: 10.1517/14712598.2015.1044894. Epub 2015 May 10. Expert Opin Biol Ther. 2015. PMID: 25959569 Free article. Review.
Gene therapy: a promising approach to treating spinal muscular atrophy.
Mulcahy PJ, Iremonger K, Karyka E, Herranz-Martín S, Shum KT, Tam JK, Azzouz M. Mulcahy PJ, et al. Among authors: herranz martin s. Hum Gene Ther. 2014 Jul;25(7):575-86. doi: 10.1089/hum.2013.186. Epub 2014 Jun 27. Hum Gene Ther. 2014. PMID: 24845847 Review.
Viral delivery of C9orf72 hexanucleotide repeat expansions in mice leads to repeat-length-dependent neuropathology and behavioural deficits.
Herranz-Martin S, Chandran J, Lewis K, Mulcahy P, Higginbottom A, Walker C, Valenzuela IMY, Jones RA, Coldicott I, Iannitti T, Akaaboune M, El-Khamisy SF, Gillingwater TH, Shaw PJ, Azzouz M. Herranz-Martin S, et al. Dis Model Mech. 2017 Jul 1;10(7):859-868. doi: 10.1242/dmm.029892. Epub 2017 May 26. Dis Model Mech. 2017. PMID: 28550099 Free PMC article.
C9orf72 expansion disrupts ATM-mediated chromosomal break repair.
Walker C, Herranz-Martin S, Karyka E, Liao C, Lewis K, Elsayed W, Lukashchuk V, Chiang SC, Ray S, Mulcahy PJ, Jurga M, Tsagakis I, Iannitti T, Chandran J, Coldicott I, De Vos KJ, Hassan MK, Higginbottom A, Shaw PJ, Hautbergue GM, Azzouz M, El-Khamisy SF. Walker C, et al. Among authors: herranz martin s. Nat Neurosci. 2017 Sep;20(9):1225-1235. doi: 10.1038/nn.4604. Epub 2017 Jul 17. Nat Neurosci. 2017. PMID: 28714954 Free PMC article.