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Methylome-based cell-of-origin modeling (Methyl-COOM) identifies aberrant expression of immune regulatory molecules in CLL.
Wierzbinska JA, Toth R, Ishaque N, Rippe K, Mallm JP, Klett LC, Mertens D, Zenz T, Hielscher T, Seifert M, Küppers R, Assenov Y, Lutsik P, Stilgenbauer S, Roessner PM, Seiffert M, Byrd J, Oakes CC, Plass C, Lipka DB. Wierzbinska JA, et al. Among authors: hielscher t. Genome Med. 2020 Mar 18;12(1):29. doi: 10.1186/s13073-020-00724-7. Genome Med. 2020. PMID: 32188505 Free PMC article.
Germline allele-specific expression of DAPK1 in chronic lymphocytic leukemia.
Wei QX, Claus R, Hielscher T, Mertens D, Raval A, Oakes CC, Tanner SM, de la Chapelle A, Byrd JC, Stilgenbauer S, Plass C. Wei QX, et al. Among authors: hielscher t. PLoS One. 2013;8(1):e55261. doi: 10.1371/journal.pone.0055261. Epub 2013 Jan 28. PLoS One. 2013. PMID: 23383130 Free PMC article.
p53-dependent non-coding RNA networks in chronic lymphocytic leukemia.
Blume CJ, Hotz-Wagenblatt A, Hüllein J, Sellner L, Jethwa A, Stolz T, Slabicki M, Lee K, Sharathchandra A, Benner A, Dietrich S, Oakes CC, Dreger P, te Raa D, Kater AP, Jauch A, Merkel O, Oren M, Hielscher T, Zenz T. Blume CJ, et al. Among authors: hielscher t. Leukemia. 2015 Oct;29(10):2015-23. doi: 10.1038/leu.2015.119. Epub 2015 May 14. Leukemia. 2015. PMID: 25971364
Gene promoter methylation signature predicts survival of head and neck squamous cell carcinoma patients.
Kostareli E, Hielscher T, Zucknick M, Baboci L, Wichmann G, Holzinger D, Mücke O, Pawlita M, Del Mistro A, Boscolo-Rizzo P, Da Mosto MC, Tirelli G, Plinkert P, Dietz A, Plass C, Weichenhan D, Hess J. Kostareli E, et al. Among authors: hielscher t. Epigenetics. 2016;11(1):61-73. doi: 10.1080/15592294.2015.1137414. Epub 2016 Jan 19. Epigenetics. 2016. PMID: 26786582 Free PMC article.
Prognostic relevance of miRNA-155 methylation in anaplastic glioma.
Schliesser MG, Claus R, Hielscher T, Grimm C, Weichenhan D, Blaes J, Wiestler B, Hau P, Schramm J, Sahm F, Weiß EK, Weiler M, Baer C, Schmidt-Graf F, Schackert G, Westphal M, Hertenstein A, Roth P, Galldiks N, Hartmann C, Pietsch T, Felsberg J, Reifenberger G, Sabel MC, Winkler F, von Deimling A, Meisner C, Vajkoczy P, Platten M, Weller M, Plass C, Wick W. Schliesser MG, et al. Among authors: hielscher t. Oncotarget. 2016 Dec 13;7(50):82028-82045. doi: 10.18632/oncotarget.13452. Oncotarget. 2016. PMID: 27880937 Free PMC article.
A PRDX1-p38α heterodimer amplifies MET-driven invasion of IDH-wildtype and IDH-mutant gliomas.
Wirthschaft P, Bode J, Simon AEM, Hoffmann E, van Laack R, Krüwel T, Dietrich F, Bucher D, Hahn A, Sahm F, Breckwoldt MO, Kurz FT, Hielscher T, Fischer B, Dross N, Ruiz de Almodovar C, von Deimling A, Herold-Mende C, Plass C, Boulant S, Wiestler B, Reifenberger G, Lichter P, Wick W, Tews B. Wirthschaft P, et al. Among authors: hielscher t. Int J Cancer. 2018 Sep 1;143(5):1176-1187. doi: 10.1002/ijc.31404. Epub 2018 Apr 16. Int J Cancer. 2018. PMID: 29582423 Free article.
IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression.
Sadik A, Somarribas Patterson LF, Öztürk S, Mohapatra SR, Panitz V, Secker PF, Pfänder P, Loth S, Salem H, Prentzell MT, Berdel B, Iskar M, Faessler E, Reuter F, Kirst I, Kalter V, Foerster KI, Jäger E, Guevara CR, Sobeh M, Hielscher T, Poschet G, Reinhardt A, Hassel JC, Zapatka M, Hahn U, von Deimling A, Hopf C, Schlichting R, Escher BI, Burhenne J, Haefeli WE, Ishaque N, Böhme A, Schäuble S, Thedieck K, Trump S, Seiffert M, Opitz CA. Sadik A, et al. Among authors: hielscher t. Cell. 2020 Sep 3;182(5):1252-1270.e34. doi: 10.1016/j.cell.2020.07.038. Epub 2020 Aug 19. Cell. 2020. PMID: 32818467 Free article.
DNA methylation biomarkers for noninvasive detection of triple-negative breast cancer using liquid biopsy.
Manoochehri M, Borhani N, Gerhäuser C, Assenov Y, Schönung M, Hielscher T, Christensen BC, Lee MK, Gröne HJ, Lipka DB, Brüning T, Brauch H, Ko YD, Hamann U. Manoochehri M, et al. Among authors: hielscher t. Int J Cancer. 2023 Mar 1;152(5):1025-1035. doi: 10.1002/ijc.34337. Epub 2022 Nov 8. Int J Cancer. 2023. PMID: 36305646 Free article. Review.
209 results