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Mitochondrial protein acetylation regulates metabolism.
Anderson KA, Hirschey MD. Anderson KA, et al. Among authors: hirschey md. Essays Biochem. 2012;52:23-35. doi: 10.1042/bse0520023. Essays Biochem. 2012. PMID: 22708561 Free PMC article. Review.
Sirtuin 3 (SIRT3) protein regulates long-chain acyl-CoA dehydrogenase by deacetylating conserved lysines near the active site.
Bharathi SS, Zhang Y, Mohsen AW, Uppala R, Balasubramani M, Schreiber E, Uechi G, Beck ME, Rardin MJ, Vockley J, Verdin E, Gibson BW, Hirschey MD, Goetzman ES. Bharathi SS, et al. Among authors: hirschey md. J Biol Chem. 2013 Nov 22;288(47):33837-33847. doi: 10.1074/jbc.M113.510354. Epub 2013 Oct 11. J Biol Chem. 2013. PMID: 24121500 Free PMC article.
Lysine glutarylation is a protein posttranslational modification regulated by SIRT5.
Tan M, Peng C, Anderson KA, Chhoy P, Xie Z, Dai L, Park J, Chen Y, Huang H, Zhang Y, Ro J, Wagner GR, Green MF, Madsen AS, Schmiesing J, Peterson BS, Xu G, Ilkayeva OR, Muehlbauer MJ, Braulke T, Mühlhausen C, Backos DS, Olsen CA, McGuire PJ, Pletcher SD, Lombard DB, Hirschey MD, Zhao Y. Tan M, et al. Among authors: hirschey md. Cell Metab. 2014 Apr 1;19(4):605-17. doi: 10.1016/j.cmet.2014.03.014. Cell Metab. 2014. PMID: 24703693 Free PMC article.
SnapShot: Mammalian Sirtuins.
Anderson KA, Green MF, Huynh FK, Wagner GR, Hirschey MD. Anderson KA, et al. Among authors: hirschey md. Cell. 2014 Nov 6;159(4):956-956.e1. doi: 10.1016/j.cell.2014.10.045. Cell. 2014. PMID: 25417168 Free PMC article.
SIRT3 regulates progression and development of diseases of aging.
McDonnell E, Peterson BS, Bomze HM, Hirschey MD. McDonnell E, et al. Among authors: hirschey md. Trends Endocrinol Metab. 2015 Sep;26(9):486-492. doi: 10.1016/j.tem.2015.06.001. Epub 2015 Jun 29. Trends Endocrinol Metab. 2015. PMID: 26138757 Free PMC article. Review.
Investigating the Sensitivity of NAD+-dependent Sirtuin Deacylation Activities to NADH.
Madsen AS, Andersen C, Daoud M, Anderson KA, Laursen JS, Chakladar S, Huynh FK, Colaço AR, Backos DS, Fristrup P, Hirschey MD, Olsen CA. Madsen AS, et al. Among authors: hirschey md. J Biol Chem. 2016 Mar 25;291(13):7128-41. doi: 10.1074/jbc.M115.668699. Epub 2016 Feb 9. J Biol Chem. 2016. PMID: 26861872 Free PMC article.
88 results