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Page 1
Brain Penetrable Inhibitors of Ceramide Galactosyltransferase for the Treatment of Lysosomal Storage Disorders.
ACS Med Chem Lett. 2020 Jun 16;11(10):2010-2016. doi: 10.1021/acsmedchemlett.0c00120. eCollection 2020 Oct 8.
ACS Med Chem Lett. 2020.
PMID: 33062186
Free PMC article.
Discovery of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid diamides that increase CFTR mediated chloride transport.
Hirth BH, Qiao S, Cuff LM, Cochran BM, Pregel MJ, Gregory JS, Sneddon SF, Kane JL Jr.
Hirth BH, et al.
Bioorg Med Chem Lett. 2005 Apr 15;15(8):2087-91. doi: 10.1016/j.bmcl.2005.02.041.
Bioorg Med Chem Lett. 2005.
PMID: 15808474
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Design and SAR of novel potassium channel openers targeted for urge urinary incontinence. 2. Selective and potent benzylamino cyclobutenediones.
Gilbert AM, Antane MM, Argentieri TM, Butera JA, Francisco GD, Freeden C, Gundersen EG, Graceffa RF, Herbst D, Hirth BH, Lennox JR, McFarlane G, Norton NW, Quagliato D, Sheldon JH, Warga D, Wojdan A, Woods M.
Gilbert AM, et al. Among authors: hirth bh.
J Med Chem. 2000 Mar 23;43(6):1203-14. doi: 10.1021/jm9905108.
J Med Chem. 2000.
PMID: 10737753
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Ureas of 5-aminopyrazole and 2-aminothiazole inhibit growth of gram-positive bacteria.
Kane JL Jr, Hirth BH, Liang B, Gourlie BB, Nahill S, Barsomian G.
Kane JL Jr, et al. Among authors: hirth bh.
Bioorg Med Chem Lett. 2003 Dec 15;13(24):4463-6. doi: 10.1016/j.bmcl.2003.09.013.
Bioorg Med Chem Lett. 2003.
PMID: 14643347
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Design and SAR of novel potassium channel openers targeted for urge urinary incontinence. 1. N-Cyanoguanidine bioisosteres possessing in vivo bladder selectivity.
Butera JA, Antane MM, Antane SA, Argentieri TM, Freeden C, Graceffa RF, Hirth BH, Jenkins D, Lennox JR, Matelan E, Norton NW, Quagliato D, Sheldon JH, Spinelli W, Warga D, Wojdan A, Woods M.
Butera JA, et al. Among authors: hirth bh.
J Med Chem. 2000 Mar 23;43(6):1187-202. doi: 10.1021/jm9905099.
J Med Chem. 2000.
PMID: 10737752
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