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6 results
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Napabucasin versus placebo in refractory advanced colorectal cancer: a randomised phase 3 trial.
Lancet Gastroenterol Hepatol. 2018 Apr;3(4):263-270. doi: 10.1016/S2468-1253(18)30009-8. Epub 2018 Feb 1.
Lancet Gastroenterol Hepatol. 2018.
PMID: 29397354
Clinical Trial.
Mass balance and pharmacokinetics of an oral dose of 14 C-napabucasin in healthy adult male subjects.
Dai X, Karol MD, Hitron M, Hard ML, Blanchard JE, Eraut NCJE, Rich N, Gufford BT.
Dai X, et al. Among authors: hitron m.
Pharmacol Res Perspect. 2021 Feb;9(1):e00722. doi: 10.1002/prp2.722.
Pharmacol Res Perspect. 2021.
PMID: 33576192
Free PMC article.
Clinical Trial.
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Ipilimumab, Pembrolizumab, or Nivolumab in Combination with BBI608 in Patients with Advanced Cancers Treated at MD Anderson Cancer Center.
Vo HH, Cartwright C, Song IW, Karp DD, Nogueras Gonzalez GM, Xie Y, Karol M, Hitron M, Vining D, Tsimberidou AM.
Vo HH, et al. Among authors: hitron m.
Cancers (Basel). 2022 Mar 4;14(5):1330. doi: 10.3390/cancers14051330.
Cancers (Basel). 2022.
PMID: 35267638
Free PMC article.
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Napabucasin Drug-Drug Interaction Potential, Safety, Tolerability, and Pharmacokinetics Following Oral Dosing in Healthy Adult Volunteers.
Dai X, Karol MD, Hitron M, Hard ML, Goulet MT, McLaughlin CF, Brantley SJ.
Dai X, et al. Among authors: hitron m.
Clin Pharmacol Drug Dev. 2021 Aug;10(8):824-839. doi: 10.1002/cpdd.961. Epub 2021 Jun 9.
Clin Pharmacol Drug Dev. 2021.
PMID: 34107166
Free PMC article.
Clinical Trial.
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Napabucasin Plus FOLFIRI in Patients With Previously Treated Metastatic Colorectal Cancer: Results From the Open-Label, Randomized Phase III CanStem303C Study.
Shah MA, Yoshino T, Tebbutt NC, Grothey A, Tabernero J, Xu RH, Cervantes A, Oh SC, Yamaguchi K, Fakih M, Falcone A, Wu C, Chiu VK, Tomasek J, Bendell J, Fontaine M, Hitron M, Xu B, Taieb J, Van Cutsem E.
Shah MA, et al. Among authors: hitron m.
Clin Colorectal Cancer. 2023 Mar;22(1):100-110. doi: 10.1016/j.clcc.2022.11.002. Epub 2022 Nov 11.
Clin Colorectal Cancer. 2023.
PMID: 36503738
Clinical Trial.
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