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210 results

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Page 1
Positive selection of somatically mutated clones identifies adaptive pathways in metabolic liver disease.
Wang Z, Zhu S, Jia Y, Wang Y, Kubota N, Fujiwara N, Gordillo R, Lewis C, Zhu M, Sharma T, Li L, Zeng Q, Lin YH, Hsieh MH, Gopal P, Wang T, Hoare M, Campbell P, Hoshida Y, Zhu H. Wang Z, et al. Among authors: hoare m. Cell. 2023 Apr 27;186(9):1968-1984.e20. doi: 10.1016/j.cell.2023.03.014. Epub 2023 Apr 10. Cell. 2023. PMID: 37040760 Free PMC article.
Somatic mutations and clonal dynamics in healthy and cirrhotic human liver.
Brunner SF, Roberts ND, Wylie LA, Moore L, Aitken SJ, Davies SE, Sanders MA, Ellis P, Alder C, Hooks Y, Abascal F, Stratton MR, Martincorena I, Hoare M, Campbell PJ. Brunner SF, et al. Among authors: hoare m. Nature. 2019 Oct;574(7779):538-542. doi: 10.1038/s41586-019-1670-9. Epub 2019 Oct 23. Nature. 2019. PMID: 31645727 Free PMC article.
Convergent somatic mutations in metabolism genes in chronic liver disease.
Ng SWK, Rouhani FJ, Brunner SF, Brzozowska N, Aitken SJ, Yang M, Abascal F, Moore L, Nikitopoulou E, Chappell L, Leongamornlert D, Ivovic A, Robinson P, Butler T, Sanders MA, Williams N, Coorens THH, Teague J, Raine K, Butler AP, Hooks Y, Wilson B, Birtchnell N, Naylor H, Davies SE, Stratton MR, Martincorena I, Rahbari R, Frezza C, Hoare M, Campbell PJ. Ng SWK, et al. Among authors: hoare m. Nature. 2021 Oct;598(7881):473-478. doi: 10.1038/s41586-021-03974-6. Epub 2021 Oct 13. Nature. 2021. PMID: 34646017
Acetyl-CoA metabolism drives epigenome change and contributes to carcinogenesis risk in fatty liver disease.
Assante G, Chandrasekaran S, Ng S, Tourna A, Chung CH, Isse KA, Banks JL, Soffientini U, Filippi C, Dhawan A, Liu M, Rozen SG, Hoare M, Campbell P, Ballard JWO, Turner N, Morris MJ, Chokshi S, Youngson NA. Assante G, et al. Among authors: hoare m. Genome Med. 2022 Jun 23;14(1):67. doi: 10.1186/s13073-022-01071-5. Genome Med. 2022. PMID: 35739588 Free PMC article.
Correction: Acetyl-CoA metabolism drives epigenome change and contributes to carcinogenesis risk in fatty liver disease.
Assante G, Chandrasekaran S, Ng S, Tourna A, Chung CH, Isse KA, Banks JL, Soffientini U, Filippi C, Dhawan A, Liu M, Rozen SG, Hoare M, Campbell P, Ballard JWO, Turner N, Morris MJ, Chokshi S, Youngson NA. Assante G, et al. Among authors: hoare m. Genome Med. 2023 May 18;15(1):38. doi: 10.1186/s13073-023-01190-7. Genome Med. 2023. PMID: 37202796 Free PMC article. No abstract available.
Selective insulin resistance in hepatocyte senescence.
Aravinthan A, Challis B, Shannon N, Hoare M, Heaney J, Alexander GJM. Aravinthan A, et al. Among authors: hoare m. Exp Cell Res. 2015 Feb 1;331(1):38-45. doi: 10.1016/j.yexcr.2014.09.025. Epub 2014 Sep 28. Exp Cell Res. 2015. PMID: 25263463
NOTCH1 mediates a switch between two distinct secretomes during senescence.
Hoare M, Ito Y, Kang TW, Weekes MP, Matheson NJ, Patten DA, Shetty S, Parry AJ, Menon S, Salama R, Antrobus R, Tomimatsu K, Howat W, Lehner PJ, Zender L, Narita M. Hoare M, et al. Nat Cell Biol. 2016 Sep;18(9):979-92. doi: 10.1038/ncb3397. Epub 2016 Aug 15. Nat Cell Biol. 2016. PMID: 27525720 Free PMC article.
210 results