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Experimental lupus is aggravated in mouse strains with impaired induction of neutrophil extracellular traps.
Kienhöfer D, Hahn J, Stoof J, Csepregi JZ, Reinwald C, Urbonaviciute V, Johnsson C, Maueröder C, Podolska MJ, Biermann MH, Leppkes M, Harrer T, Hultqvist M, Olofsson P, Munoz LE, Mocsai A, Herrmann M, Schett G, Holmdahl R, Hoffmann MH. Kienhöfer D, et al. Among authors: hoffmann mh. JCI Insight. 2017 May 18;2(10):e92920. doi: 10.1172/jci.insight.92920. eCollection 2017 May 18. JCI Insight. 2017. PMID: 28515366 Free PMC article.
No evidence of pathogenic involvement of cathelicidins in patient cohorts and mouse models of lupus and arthritis.
Kienhöfer D, Hahn J, Schubert I, Reinwald C, Ipseiz N, Lang SC, Borràs ÈB, Amann K, Sjöwall C, Barron AE, Hueber AJ, Agerberth B, Schett G, Hoffmann MH. Kienhöfer D, et al. Among authors: hoffmann mh. PLoS One. 2014 Dec 23;9(12):e115474. doi: 10.1371/journal.pone.0115474. eCollection 2014. PLoS One. 2014. PMID: 25535966 Free PMC article.
Externalized decondensed neutrophil chromatin occludes pancreatic ducts and drives pancreatitis.
Leppkes M, Maueröder C, Hirth S, Nowecki S, Günther C, Billmeier U, Paulus S, Biermann M, Munoz LE, Hoffmann M, Wildner D, Croxford AL, Waisman A, Mowen K, Jenne DE, Krenn V, Mayerle J, Lerch MM, Schett G, Wirtz S, Neurath MF, Herrmann M, Becker C. Leppkes M, et al. Nat Commun. 2016 Mar 11;7:10973. doi: 10.1038/ncomms10973. Nat Commun. 2016. PMID: 26964500 Free PMC article.
Animal Models of Rheumatoid Arthritis (I): Pristane-Induced Arthritis in the Rat.
Tuncel J, Haag S, Hoffmann MH, Yau AC, Hultqvist M, Olofsson P, Bäcklund J, Nandakumar KS, Weidner D, Fischer A, Leichsenring A, Lange F, Haase C, Lu S, Gulko PS, Steiner G, Holmdahl R. Tuncel J, et al. Among authors: hoffmann mh. PLoS One. 2016 May 26;11(5):e0155936. doi: 10.1371/journal.pone.0155936. eCollection 2016. PLoS One. 2016. PMID: 27227821 Free PMC article.
121 results