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The glucose-dependent insulinotropic polypeptide (GIP) regulates body weight and food intake via CNS-GIPR signaling.
Zhang Q, Delessa CT, Augustin R, Bakhti M, Colldén G, Drucker DJ, Feuchtinger A, Caceres CG, Grandl G, Harger A, Herzig S, Hofmann S, Holleman CL, Jastroch M, Keipert S, Kleinert M, Knerr PJ, Kulaj K, Legutko B, Lickert H, Liu X, Luippold G, Lutter D, Malogajski E, Medina MT, Mowery SA, Blutke A, Perez-Tilve D, Salinno C, Sehrer L, DiMarchi RD, Tschöp MH, Stemmer K, Finan B, Wolfrum C, Müller TD. Zhang Q, et al. Among authors: hofmann s. Cell Metab. 2021 Apr 6;33(4):833-844.e5. doi: 10.1016/j.cmet.2021.01.015. Epub 2021 Feb 10. Cell Metab. 2021. PMID: 33571454 Free PMC article.
The central melanocortin system directly controls peripheral lipid metabolism.
Nogueiras R, Wiedmer P, Perez-Tilve D, Veyrat-Durebex C, Keogh JM, Sutton GM, Pfluger PT, Castaneda TR, Neschen S, Hofmann SM, Howles PN, Morgan DA, Benoit SC, Szanto I, Schrott B, Schürmann A, Joost HG, Hammond C, Hui DY, Woods SC, Rahmouni K, Butler AA, Farooqi IS, O'Rahilly S, Rohner-Jeanrenaud F, Tschöp MH. Nogueiras R, et al. Among authors: hofmann sm. J Clin Invest. 2007 Nov;117(11):3475-88. doi: 10.1172/JCI31743. J Clin Invest. 2007. PMID: 17885689 Free PMC article.
Dietary sugars: a fat difference.
Hofmann SM, Tschöp MH. Hofmann SM, et al. J Clin Invest. 2009 May;119(5):1089-92. doi: 10.1172/jci39332. J Clin Invest. 2009. PMID: 19422101 Free PMC article.
A new glucagon and GLP-1 co-agonist eliminates obesity in rodents.
Day JW, Ottaway N, Patterson JT, Gelfanov V, Smiley D, Gidda J, Findeisen H, Bruemmer D, Drucker DJ, Chaudhary N, Holland J, Hembree J, Abplanalp W, Grant E, Ruehl J, Wilson H, Kirchner H, Lockie SH, Hofmann S, Woods SC, Nogueiras R, Pfluger PT, Perez-Tilve D, DiMarchi R, Tschöp MH. Day JW, et al. Among authors: hofmann s. Nat Chem Biol. 2009 Oct;5(10):749-57. doi: 10.1038/nchembio.209. Epub 2009 Jul 13. Nat Chem Biol. 2009. PMID: 19597507
Melanocortin signaling in the CNS directly regulates circulating cholesterol.
Perez-Tilve D, Hofmann SM, Basford J, Nogueiras R, Pfluger PT, Patterson JT, Grant E, Wilson-Perez HE, Granholm NA, Arnold M, Trevaskis JL, Butler AA, Davidson WS, Woods SC, Benoit SC, Sleeman MW, DiMarchi RD, Hui DY, Tschöp MH. Perez-Tilve D, et al. Among authors: hofmann sm. Nat Neurosci. 2010 Jul;13(7):877-82. doi: 10.1038/nn.2569. Epub 2010 Jun 6. Nat Neurosci. 2010. PMID: 20526334 Free PMC article.
CNS regulation of plasma cholesterol.
Perez-Tilve D, Davidson WS, Tschöp M, Hofmann SM. Perez-Tilve D, et al. Ann Med. 2012 Nov;44(7):656-63. doi: 10.3109/07853890.2011.590819. Epub 2011 Jul 4. Ann Med. 2012. PMID: 21726126 Review.
Neural regulation of cholesterol metabolism.
Perez-Tilve D, Habbeger KM, Tschöp MH, Hofmann SM. Perez-Tilve D, et al. Curr Opin Lipidol. 2011 Aug;22(4):283-7. doi: 10.1097/MOL.0b013e328348a459. Curr Opin Lipidol. 2011. PMID: 21734571 Review.
1,477 results