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The B cell mutator AID promotes B lymphoid blast crisis and drug resistance in chronic myeloid leukemia.
Klemm L, Duy C, Iacobucci I, Kuchen S, von Levetzow G, Feldhahn N, Henke N, Li Z, Hoffmann TK, Kim YM, Hofmann WK, Jumaa H, Groffen J, Heisterkamp N, Martinelli G, Lieber MR, Casellas R, Müschen M. Klemm L, et al. Among authors: hofmann wk. Cancer Cell. 2009 Sep 8;16(3):232-45. doi: 10.1016/j.ccr.2009.07.030. Cancer Cell. 2009. PMID: 19732723 Free PMC article.
Deficiency of Bruton's tyrosine kinase in B cell precursor leukemia cells.
Feldhahn N, Río P, Soh BN, Liedtke S, Sprangers M, Klein F, Wernet P, Jumaa H, Hofmann WK, Hanenberg H, Rowley JD, Müschen M. Feldhahn N, et al. Among authors: hofmann wk. Proc Natl Acad Sci U S A. 2005 Sep 13;102(37):13266-71. doi: 10.1073/pnas.0505196102. Epub 2005 Sep 2. Proc Natl Acad Sci U S A. 2005. PMID: 16141323 Free PMC article.
Pre-B cell receptor-mediated cell cycle arrest in Philadelphia chromosome-positive acute lymphoblastic leukemia requires IKAROS function.
Trageser D, Iacobucci I, Nahar R, Duy C, von Levetzow G, Klemm L, Park E, Schuh W, Gruber T, Herzog S, Kim YM, Hofmann WK, Li A, Storlazzi CT, Jäck HM, Groffen J, Martinelli G, Heisterkamp N, Jumaa H, Müschen M. Trageser D, et al. Among authors: hofmann wk. J Exp Med. 2009 Aug 3;206(8):1739-53. doi: 10.1084/jem.20090004. Epub 2009 Jul 20. J Exp Med. 2009. PMID: 19620627 Free PMC article.
SNP array analysis of tyrosine kinase inhibitor-resistant chronic myeloid leukemia identifies heterogeneous secondary genomic alterations.
Nowak D, Ogawa S, Müschen M, Kato M, Kawamata N, Meixel A, Nowak V, Kim HS, Kang S, Paquette R, Chang MS, Thoennissen NH, Mossner M, Hofmann WK, Kohlmann A, Weiss T, Haferlach T, Haferlach C, Koeffler HP. Nowak D, et al. Among authors: hofmann wk. Blood. 2010 Feb 4;115(5):1049-53. doi: 10.1182/blood-2009-03-210377. Epub 2009 Dec 2. Blood. 2010. PMID: 19965645 Free PMC article.
BCL6 enables Ph+ acute lymphoblastic leukaemia cells to survive BCR-ABL1 kinase inhibition.
Duy C, Hurtz C, Shojaee S, Cerchietti L, Geng H, Swaminathan S, Klemm L, Kweon SM, Nahar R, Braig M, Park E, Kim YM, Hofmann WK, Herzog S, Jumaa H, Koeffler HP, Yu JJ, Heisterkamp N, Graeber TG, Wu H, Ye BH, Melnick A, Müschen M. Duy C, et al. Among authors: hofmann wk. Nature. 2011 May 19;473(7347):384-8. doi: 10.1038/nature09883. Nature. 2011. PMID: 21593872 Free PMC article.
Targeting survivin overcomes drug resistance in acute lymphoblastic leukemia.
Park E, Gang EJ, Hsieh YT, Schaefer P, Chae S, Klemm L, Huantes S, Loh M, Conway EM, Kang ES, Hoe Koo H, Hofmann WK, Heisterkamp N, Pelus L, Keerthivasan G, Crispino J, Kahn M, Müschen M, Kim YM. Park E, et al. Among authors: hofmann wk. Blood. 2011 Aug 25;118(8):2191-9. doi: 10.1182/blood-2011-04-351239. Epub 2011 Jun 28. Blood. 2011. PMID: 21715311 Free PMC article.
395 results