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Telomerase mRNA Enhances Human Skin Engraftment for Wound Healing.
Chang DF, Court KA, Holgate R, Davis EA, Bush KA, Quick AP, Spiegel AJ, Rahimi M, Cooke JP, Godin B. Chang DF, et al. Among authors: holgate r. Adv Healthc Mater. 2024 Jan;13(2):e2302029. doi: 10.1002/adhm.202302029. Epub 2023 Aug 31. Adv Healthc Mater. 2024. PMID: 37619534
Selective blood-brain barrier permeabilization of brain metastases by a type 1 receptor-selective tumor necrosis factor mutein.
Munoz Pinto MF, Campbell SJ, Simoglou Karali C, Johanssen VA, Bristow C, Cheng VWT, Zarghami N, Larkin JR, Pannell M, Hearn A, Chui C, Brinquis Nunez B, Bokma E, Holgate R, Anthony DC, Sibson NR. Munoz Pinto MF, et al. Among authors: holgate r. Neuro Oncol. 2022 Jan 5;24(1):52-63. doi: 10.1093/neuonc/noab177. Neuro Oncol. 2022. PMID: 34297105 Free PMC article.
Redefining IL11 as a regeneration-limiting hepatotoxin and therapeutic target in acetaminophen-induced liver injury.
Widjaja AA, Dong J, Adami E, Viswanathan S, Ng B, Pakkiri LS, Chothani SP, Singh BK, Lim WW, Zhou J, Shekeran SG, Tan J, Lim SY, Goh J, Wang M, Holgate R, Hearn A, Felkin LE, Yen PM, Dear JW, Drum CL, Schafer S, Cook SA. Widjaja AA, et al. Among authors: holgate r. Sci Transl Med. 2021 Jun 9;13(597):eaba8146. doi: 10.1126/scitranslmed.aba8146. Sci Transl Med. 2021. PMID: 34108253
ARGX-117, a therapeutic complement inhibiting antibody targeting C2.
Van de Walle I, Silence K, Budding K, Van de Ven L, Dijkxhoorn K, de Zeeuw E, Yildiz C, Gabriels S, Percier JM, Wildemann J, Meeldijk J, Simons PJ, Boon L, Cox L, Holgate R, Urbanus R, Otten HG, Leusen JHW, Blanchetot C, de Haard H, Hack CE, Boross P. Van de Walle I, et al. Among authors: holgate r. J Allergy Clin Immunol. 2021 Apr;147(4):1420-1429.e7. doi: 10.1016/j.jaci.2020.08.028. Epub 2020 Sep 11. J Allergy Clin Immunol. 2021. PMID: 32926878 Free PMC article.
Blocking FcRn in humans reduces circulating IgG levels and inhibits IgG immune complex-mediated immune responses.
Blumberg LJ, Humphries JE, Jones SD, Pearce LB, Holgate R, Hearn A, Cheung J, Mahmood A, Del Tito B, Graydon JS, Stolz LE, Bitonti A, Purohit S, de Graaf D, Kacena K, Andersen JT, Christianson GJ, Roopenian DC, Hubbard JJ, Gandhi AK, Lasseter K, Pyzik M, Blumberg RS. Blumberg LJ, et al. Among authors: holgate r. Sci Adv. 2019 Dec 18;5(12):eaax9586. doi: 10.1126/sciadv.aax9586. eCollection 2019 Dec. Sci Adv. 2019. PMID: 31897428 Free PMC article. Clinical Trial.
A powered prosthetic ankle joint for walking and running.
Grimmer M, Holgate M, Holgate R, Boehler A, Ward J, Hollander K, Sugar T, Seyfarth A. Grimmer M, et al. Among authors: holgate r. Biomed Eng Online. 2016 Dec 19;15(Suppl 3):141. doi: 10.1186/s12938-016-0286-7. Biomed Eng Online. 2016. PMID: 28105953 Free PMC article.
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