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113 results

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Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.
Trynka G, Zhernakova A, Romanos J, Franke L, Hunt KA, Turner G, Bruinenberg M, Heap GA, Platteel M, Ryan AW, de Kovel C, Holmes GK, Howdle PD, Walters JR, Sanders DS, Mulder CJ, Mearin ML, Verbeek WH, Trimble V, Stevens FM, Kelleher D, Barisani D, Bardella MT, McManus R, van Heel DA, Wijmenga C. Trynka G, et al. Among authors: holmes gk. Gut. 2009 Aug;58(8):1078-83. doi: 10.1136/gut.2008.169052. Epub 2009 Feb 24. Gut. 2009. PMID: 19240061
A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21.
van Heel DA, Franke L, Hunt KA, Gwilliam R, Zhernakova A, Inouye M, Wapenaar MC, Barnardo MC, Bethel G, Holmes GK, Feighery C, Jewell D, Kelleher D, Kumar P, Travis S, Walters JR, Sanders DS, Howdle P, Swift J, Playford RJ, McLaren WM, Mearin ML, Mulder CJ, McManus R, McGinnis R, Cardon LR, Deloukas P, Wijmenga C. van Heel DA, et al. Among authors: holmes gk. Nat Genet. 2007 Jul;39(7):827-9. doi: 10.1038/ng2058. Epub 2007 Jun 10. Nat Genet. 2007. PMID: 17558408 Free PMC article.
Newly identified genetic risk variants for celiac disease related to the immune response.
Hunt KA, Zhernakova A, Turner G, Heap GA, Franke L, Bruinenberg M, Romanos J, Dinesen LC, Ryan AW, Panesar D, Gwilliam R, Takeuchi F, McLaren WM, Holmes GK, Howdle PD, Walters JR, Sanders DS, Playford RJ, Trynka G, Mulder CJ, Mearin ML, Verbeek WH, Trimble V, Stevens FM, O'Morain C, Kennedy NP, Kelleher D, Pennington DJ, Strachan DP, McArdle WL, Mein CA, Wapenaar MC, Deloukas P, McGinnis R, McManus R, Wijmenga C, van Heel DA. Hunt KA, et al. Among authors: holmes gk. Nat Genet. 2008 Apr;40(4):395-402. doi: 10.1038/ng.102. Epub 2008 Mar 2. Nat Genet. 2008. PMID: 18311140 Free PMC article.
Small bowel malignancy in coeliac disease.
Howdle PD, Holmes GK. Howdle PD, et al. Among authors: holmes gk. Gut. 2004 Mar;53(3):470. Gut. 2004. PMID: 14960543 Free PMC article. No abstract available.
Variation in the CTLA4/CD28 gene region confers an increased risk of coeliac disease.
Popat S, Hearle N, Hogberg L, Braegger CP, O'Donoghue D, Falth-Magnusson K, Holmes GK, Howdle PD, Jenkins H, Johnston S, Kennedy NP, Kumar PJ, Logan RF, Marsh MN, Mulder CJ, Torinsson Naluai A, Sjoberg K, Stenhammar L, Walters JR, Jewell DP, Houlston RS. Popat S, et al. Among authors: holmes gk. Ann Hum Genet. 2002 Mar;66(Pt 2):125-37. doi: 10.1017/S0003480002001021. Ann Hum Genet. 2002. PMID: 12174216 Review.
Contribution of the MHC region to the familial risk of coeliac disease.
Bevan S, Popat S, Braegger CP, Busch A, O'Donoghue D, Falth-Magnusson K, Ferguson A, Godkin A, Hogberg L, Holmes G, Hosie KB, Howdle PD, Jenkins H, Jewell D, Johnston S, Kennedy NP, Kerr G, Kumar P, Logan RF, Love AH, Marsh M, Mulder CJ, Sjoberg K, Stenhammer L, Walker-Smith J, Marossy AM, Houlston RS. Bevan S, et al. J Med Genet. 1999 Sep;36(9):687-90. J Med Genet. 1999. PMID: 10507725 Free PMC article.
Genome screening of coeliac disease.
Popat S, Bevan S, Braegger CP, Busch A, O'Donoghue D, Falth-Magnusson K, Godkin A, Hogberg L, Holmes G, Hosie KB, Howdle PD, Jenkins H, Jewell D, Johnston S, Kennedy NP, Kumar P, Logan RF, Love AH, Marsh MN, Mulder CJ, Sjoberg K, Stenhammar L, Walker-Smith J, Houlston RS. Popat S, et al. J Med Genet. 2002 May;39(5):328-31. doi: 10.1136/jmg.39.5.328. J Med Genet. 2002. PMID: 12011149 Free PMC article. No abstract available.
113 results