Holt D - Search Results

1

Sequence analysis and functional characterization of the violacein biosynthetic pathway from Chromobacterium violaceum.

August PR, Grossman TH, Minor C, Draper MP, MacNeil IA, Pemberton JM, Call KM, Holt D, Osburne MS. August PR, et al. Among authors: holt d. J Mol Microbiol Biotechnol. 2000 Oct;2(4):513-9. J Mol Microbiol Biotechnol. 2000. PMID: 11075927

2

Expression and isolation of antimicrobial small molecules from soil DNA libraries.

MacNeil IA, Tiong CL, Minor C, August PR, Grossman TH, Loiacono KA, Lynch BA, Phillips T, Narula S, Sundaramoorthi R, Tyler A, Aldredge T, Long H, Gilman M, Holt D, Osburne MS. MacNeil IA, et al. Among authors: holt d. J Mol Microbiol Biotechnol. 2001 Apr;3(2):301-8. J Mol Microbiol Biotechnol. 2001. PMID: 11321587

3

Simultaneous assay of Src SH3 and SH2 domain binding using different wavelength fluorescence polarization probes.

Lynch BA, Minor C, Loiacono KA, van Schravendijk MR, Ram MK, Sundaramoorthi R, Adams SE, Phillips T, Holt D, Rickles RJ, MacNeil IA. Lynch BA, et al. Among authors: holt d. Anal Biochem. 1999 Nov 1;275(1):62-73. doi: 10.1006/abio.1999.4305. Anal Biochem. 1999. PMID: 10542110

4

Structure-activity relationships of a novel class of Src SH2 inhibitors.

Buchanan JL, Vu CB, Merry TJ, Corpuz EG, Pradeepan SG, Mani UN, Yang M, Plake HR, Varkhedkar VM, Lynch BA, MacNeil IA, Loiacono KA, Tiong CL, Holt DA. Buchanan JL, et al. Among authors: holt da. Bioorg Med Chem Lett. 1999 Aug 16;9(16):2359-64. doi: 10.1016/s0960-894x(99)00389-3. Bioorg Med Chem Lett. 1999. PMID: 10476869

5

A Src SH2 selective binding compound inhibits osteoclast-mediated resorption.

Violette SM, Shakespeare WC, Bartlett C, Guan W, Smith JA, Rickles RJ, Bohacek RS, Holt DA, Baron R, Sawyer TK. Violette SM, et al. Among authors: holt da. Chem Biol. 2000 Mar;7(3):225-35. doi: 10.1016/s1074-5521(00)00090-9. Chem Biol. 2000. PMID: 10712930

6

Selective epimerization of rapamycin via a retroaldol/aldol mechanism mediated by titanium tetraisopropoxide.

Yang W, Digits CA, Hatada M, Narula S, Rozamus LW, Huestis CM, Wong J, Dalgarno D, Holt DA. Yang W, et al. Among authors: holt da. Org Lett. 1999 Dec 16;1(12):2033-5. doi: 10.1021/ol991209o. Org Lett. 1999. PMID: 10905864

7

Structure-based design and synthesis of a novel class of Src SH2 inhibitors.

Buchanan JL, Bohacek RS, Luke GP, Hatada M, Lu X, Dalgarno DC, Narula SS, Yuan R, Holt DA. Buchanan JL, et al. Among authors: holt da. Bioorg Med Chem Lett. 1999 Aug 16;9(16):2353-8. doi: 10.1016/s0960-894x(99)00388-1. Bioorg Med Chem Lett. 1999. PMID: 10476868

8

An efficient synthesis of a 4'-phosphonodifluoromethyl-3'-formyl-phenylalanine containing SRC SH2 ligand.

Shakespeare WC, Bohacek RS, Narula SS, Azimioara MD, Yuan RW, Dalgarno DC, Madden L, Botfield MC, Holt DA. Shakespeare WC, et al. Among authors: holt da. Bioorg Med Chem Lett. 1999 Nov 1;9(21):3109-12. doi: 10.1016/s0960-894x(99)00545-4. Bioorg Med Chem Lett. 1999. PMID: 10560734

9

Investigating protein-ligand interactions with a mutant FKBP possessing a designed specificity pocket.

Yang W, Rozamus LW, Narula S, Rollins CT, Yuan R, Andrade LJ, Ram MK, Phillips TB, van Schravendijk MR, Dalgarno D, Clackson T, Holt DA. Yang W, et al. Among authors: holt da. J Med Chem. 2000 Mar 23;43(6):1135-42. doi: 10.1021/jm9904396. J Med Chem. 2000. PMID: 10737745

10

Synthesis and activity of bivalent FKBP12 ligands for the regulated dimerization of proteins.

Keenan T, Yaeger DR, Courage NL, Rollins CT, Pavone ME, Rivera VM, Yang W, Guo T, Amara JF, Clackson T, Gilman M, Holt DA. Keenan T, et al. Among authors: holt da. Bioorg Med Chem. 1998 Aug;6(8):1309-35. doi: 10.1016/s0968-0896(98)00125-4. Bioorg Med Chem. 1998. PMID: 9784872

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