Holtzman DM - Search Results

1

Critical role of astroglial apolipoprotein E and liver X receptor-α expression for microglial Aβ phagocytosis.

Terwel D, Steffensen KR, Verghese PB, Kummer MP, Gustafsson JÅ, Holtzman DM, Heneka MT. Terwel D, et al. Among authors: holtzman dm. J Neurosci. 2011 May 11;31(19):7049-59. doi: 10.1523/JNEUROSCI.6546-10.2011. J Neurosci. 2011. PMID: 21562267 Free PMC article.

2

Glial fibrillary acidic protein-apolipoprotein E (apoE) transgenic mice: astrocyte-specific expression and differing biological effects of astrocyte-secreted apoE3 and apoE4 lipoproteins.

Sun Y, Wu S, Bu G, Onifade MK, Patel SN, LaDu MJ, Fagan AM, Holtzman DM. Sun Y, et al. Among authors: holtzman dm. J Neurosci. 1998 May 1;18(9):3261-72. doi: 10.1523/JNEUROSCI.18-09-03261.1998. J Neurosci. 1998. PMID: 9547235 Free PMC article.

3

Apolipoprotein E facilitates neuritic and cerebrovascular plaque formation in an Alzheimer's disease model.

Holtzman DM, Fagan AM, Mackey B, Tenkova T, Sartorius L, Paul SM, Bales K, Ashe KH, Irizarry MC, Hyman BT. Holtzman DM, et al. Ann Neurol. 2000 Jun;47(6):739-47. Ann Neurol. 2000. PMID: 10852539

4

Role of apoe/Abeta interactions in the pathogenesis of Alzheimer's disease and cerebral amyloid angiopathy.

Holtzman DM. Holtzman DM. J Mol Neurosci. 2001 Oct;17(2):147-55. doi: 10.1385/JMN:17:2:147. J Mol Neurosci. 2001. PMID: 11816788 Review.

5

Apolipoprotein E4 influences amyloid deposition but not cell loss after traumatic brain injury in a mouse model of Alzheimer's disease.

Hartman RE, Laurer H, Longhi L, Bales KR, Paul SM, McIntosh TK, Holtzman DM. Hartman RE, et al. Among authors: holtzman dm. J Neurosci. 2002 Dec 1;22(23):10083-7. doi: 10.1523/JNEUROSCI.22-23-10083.2002. J Neurosci. 2002. PMID: 12451108 Free PMC article.

6

Apolipoprotein E markedly facilitates age-dependent cerebral amyloid angiopathy and spontaneous hemorrhage in amyloid precursor protein transgenic mice.

Fryer JD, Taylor JW, DeMattos RB, Bales KR, Paul SM, Parsadanian M, Holtzman DM. Fryer JD, et al. Among authors: holtzman dm. J Neurosci. 2003 Aug 27;23(21):7889-96. doi: 10.1523/JNEUROSCI.23-21-07889.2003. J Neurosci. 2003. PMID: 12944519 Free PMC article.

7

In vivo assessment of brain interstitial fluid with microdialysis reveals plaque-associated changes in amyloid-beta metabolism and half-life.

Cirrito JR, May PC, O'Dell MA, Taylor JW, Parsadanian M, Cramer JW, Audia JE, Nissen JS, Bales KR, Paul SM, DeMattos RB, Holtzman DM. Cirrito JR, et al. Among authors: holtzman dm. J Neurosci. 2003 Oct 1;23(26):8844-53. doi: 10.1523/JNEUROSCI.23-26-08844.2003. J Neurosci. 2003. PMID: 14523085 Free PMC article.

8

Apolipoprotein E isoform-specific regulation of dendritic spine morphology in apolipoprotein E transgenic mice and Alzheimer's disease patients.

Ji Y, Gong Y, Gan W, Beach T, Holtzman DM, Wisniewski T. Ji Y, et al. Among authors: holtzman dm. Neuroscience. 2003;122(2):305-15. doi: 10.1016/j.neuroscience.2003.08.007. Neuroscience. 2003. PMID: 14614898

9

A synthetic peptide blocking the apolipoprotein E/beta-amyloid binding mitigates beta-amyloid toxicity and fibril formation in vitro and reduces beta-amyloid plaques in transgenic mice.

Sadowski M, Pankiewicz J, Scholtzova H, Ripellino JA, Li Y, Schmidt SD, Mathews PM, Fryer JD, Holtzman DM, Sigurdsson EM, Wisniewski T. Sadowski M, et al. Among authors: holtzman dm. Am J Pathol. 2004 Sep;165(3):937-48. doi: 10.1016/s0002-9440(10)63355-x. Am J Pathol. 2004. PMID: 15331417 Free PMC article.

10

Human apolipoprotein E4 alters the amyloid-beta 40:42 ratio and promotes the formation of cerebral amyloid angiopathy in an amyloid precursor protein transgenic model.

Fryer JD, Simmons K, Parsadanian M, Bales KR, Paul SM, Sullivan PM, Holtzman DM. Fryer JD, et al. Among authors: holtzman dm. J Neurosci. 2005 Mar 16;25(11):2803-10. doi: 10.1523/JNEUROSCI.5170-04.2005. J Neurosci. 2005. PMID: 15772340 Free PMC article.

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