Holwerda U - Search Results

1

5-Fluorouracil incorporation into RNA and DNA in relation to thymidylate synthase inhibition of human colorectal cancers.

Noordhuis P, Holwerda U, Van der Wilt CL, Van Groeningen CJ, Smid K, Meijer S, Pinedo HM, Peters GJ. Noordhuis P, et al. Among authors: holwerda u. Ann Oncol. 2004 Jul;15(7):1025-32. doi: 10.1093/annonc/mdh264. Ann Oncol. 2004. PMID: 15205195 Free article. Clinical Trial.

2

Quantification of 5-fluorouracil incorporation into RNA of human and murine tumors as measured with a sensitive gas chromatography-mass spectrometry assay.

Peters GJ, Noordhuis P, Komissarov A, Holwerda U, Kok M, Van Laar JA, Van der Wilt CL, Van Groeningen V, Pinedo HM. Peters GJ, et al. Among authors: holwerda u. Anal Biochem. 1995 Oct 10;231(1):157-63. doi: 10.1006/abio.1995.1515. Anal Biochem. 1995. PMID: 8678295

3

A non-radioactive sensitive assay to measure 5-fluorouracil incorporation into DNA of solid tumors.

Noordhuis P, Holwerda U, Van Laar JA, Van der Wilt CL, Peters GJ. Noordhuis P, et al. Among authors: holwerda u. Nucleosides Nucleotides Nucleic Acids. 2004 Oct;23(8-9):1481-4. doi: 10.1081/NCN-200027699. Nucleosides Nucleotides Nucleic Acids. 2004. PMID: 15571281

4

The effect of food on the pharmacokinetics of S-1 after single oral administration to patients with solid tumors.

Peters GJ, Noordhuis P, Van Groeningen CJ, Giaccone G, Holwerda U, Voorn D, Schrijvers A, Schornagel JH, Beijnen JH, Fumoleau P, Schellens JH. Peters GJ, et al. Among authors: holwerda u. Clin Cancer Res. 2004 Jun 15;10(12 Pt 1):4072-6. doi: 10.1158/1078-0432.CCR-1076-03. Clin Cancer Res. 2004. PMID: 15217941 Clinical Trial.

5

Pharmacokinetics of S-1, an oral formulation of ftorafur, oxonic acid and 5-chloro-2,4-dihydroxypyridine (molar ratio 1:0.4:1) in patients with solid tumors.

Peters GJ, Noordhuis P, Van Kuilenburg AB, Schornagel JH, Gall H, Turner SL, Swart MS, Voorn D, Van Gennip AH, Wanders J, Holwerda U, Smid K, Giaccone G, Fumoleau P, Van Groeningen CJ. Peters GJ, et al. Among authors: holwerda u. Cancer Chemother Pharmacol. 2003 Jul;52(1):1-12. doi: 10.1007/s00280-003-0617-9. Epub 2003 May 9. Cancer Chemother Pharmacol. 2003. PMID: 12739060 Clinical Trial.

6

Time dependence of the selective modulation of cisplatin-induced nephrotoxicity by WR2721 in the mouse.

Treskes M, Boven E, Holwerda U, Pinedo HM, van der Vijgh WJ. Treskes M, et al. Among authors: holwerda u. Cancer Res. 1992 Apr 15;52(8):2257-60. Cancer Res. 1992. PMID: 1313740

7

The reversal of cisplatin-protein interactions by the modulating agent WR2721 and its metabolites WR1065 and WR33278.

Treskes M, Holwerda U, Nijtmans LG, Pinedo HM, van der Vijgh WJ. Treskes M, et al. Among authors: holwerda u. Cancer Chemother Pharmacol. 1992;29(6):467-70. doi: 10.1007/BF00684849. Cancer Chemother Pharmacol. 1992. PMID: 1314713

8

The chemical reactivity of the modulating agent WR2721 (ethiofos) and its main metabolites with the antitumor agents cisplatin and carboplatin.

Treskes M, Holwerda U, Klein I, Pinedo HM, van der Vijgh WJ. Treskes M, et al. Among authors: holwerda u. Biochem Pharmacol. 1991 Nov 6;42(11):2125-30. doi: 10.1016/0006-2952(91)90347-8. Biochem Pharmacol. 1991. PMID: 1659819

9

Guanidinoacetate Methyltransferase Activity in Lymphocytes, for a Fast Diagnosis.

Berends LM, Struys EA, Roos B, Holwerda U, Jansen EEW, Salomons GS, Wamelink MMC. Berends LM, et al. Among authors: holwerda u. JIMD Rep. 2017;37:13-17. doi: 10.1007/8904_2017_4. Epub 2017 Feb 21. JIMD Rep. 2017. PMID: 28220408 Free PMC article.

10

N-acetylaspartylglutamate in CNS hypomyelination.

Wamelink MM, Struys E, Holwerda U, Sistermans EA, van Spaendonk RM, Halley D, Willemsen MA, Jakobs C, van der Knaap MS, Wolf NI. Wamelink MM, et al. Among authors: holwerda u. Neuropediatrics. 2011 Feb;42(2):74-7. doi: 10.1055/s-0031-1277176. Epub 2011 May 3. Neuropediatrics. 2011. PMID: 21544765

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