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GABAA receptor alpha 4 subunits mediate extrasynaptic inhibition in thalamus and dentate gyrus and the action of gaboxadol.
Chandra D, Jia F, Liang J, Peng Z, Suryanarayanan A, Werner DF, Spigelman I, Houser CR, Olsen RW, Harrison NL, Homanics GE. Chandra D, et al. Among authors: homanics ge. Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15230-5. doi: 10.1073/pnas.0604304103. Epub 2006 Sep 27. Proc Natl Acad Sci U S A. 2006. PMID: 17005728 Free PMC article.
Mice devoid of gamma-aminobutyrate type A receptor beta3 subunit have epilepsy, cleft palate, and hypersensitive behavior.
Homanics GE, DeLorey TM, Firestone LL, Quinlan JJ, Handforth A, Harrison NL, Krasowski MD, Rick CE, Korpi ER, Mäkelä R, Brilliant MH, Hagiwara N, Ferguson C, Snyder K, Olsen RW. Homanics GE, et al. Proc Natl Acad Sci U S A. 1997 Apr 15;94(8):4143-8. doi: 10.1073/pnas.94.8.4143. Proc Natl Acad Sci U S A. 1997. PMID: 9108119 Free PMC article.
Mice lacking the beta3 subunit of the GABAA receptor have the epilepsy phenotype and many of the behavioral characteristics of Angelman syndrome.
DeLorey TM, Handforth A, Anagnostaras SG, Homanics GE, Minassian BA, Asatourian A, Fanselow MS, Delgado-Escueta A, Ellison GD, Olsen RW. DeLorey TM, et al. Among authors: homanics ge. J Neurosci. 1998 Oct 15;18(20):8505-14. doi: 10.1523/JNEUROSCI.18-20-08505.1998. J Neurosci. 1998. PMID: 9763493 Free PMC article.
Attenuated sensitivity to neuroactive steroids in gamma-aminobutyrate type A receptor delta subunit knockout mice.
Mihalek RM, Banerjee PK, Korpi ER, Quinlan JJ, Firestone LL, Mi ZP, Lagenaur C, Tretter V, Sieghart W, Anagnostaras SG, Sage JR, Fanselow MS, Guidotti A, Spigelman I, Li Z, DeLorey TM, Olsen RW, Homanics GE. Mihalek RM, et al. Among authors: homanics ge. Proc Natl Acad Sci U S A. 1999 Oct 26;96(22):12905-10. doi: 10.1073/pnas.96.22.12905. Proc Natl Acad Sci U S A. 1999. PMID: 10536021 Free PMC article.
198 results