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Tumor penetrating peptides inhibiting MYC as a potent targeted therapeutic strategy for triple-negative breast cancers.
Wang E, Sorolla A, Cunningham PT, Bogdawa HM, Beck S, Golden E, Dewhurst RE, Florez L, Cruickshank MN, Hoffmann K, Hopkins RM, Kim J, Woo AJ, Watt PM, Blancafort P. Wang E, et al. Among authors: hopkins rm. Oncogene. 2019 Jan;38(1):140-150. doi: 10.1038/s41388-018-0421-y. Epub 2018 Aug 3. Oncogene. 2019. PMID: 30076412 Free PMC article.
GFP-complementation assay to detect functional CPP and protein delivery into living cells.
Milech N, Longville BA, Cunningham PT, Scobie MN, Bogdawa HM, Winslow S, Anastasas M, Connor T, Ong F, Stone SR, Kerfoot M, Heinrich T, Kroeger KM, Tan YF, Hoffmann K, Thomas WR, Watt PM, Hopkins RM. Milech N, et al. Among authors: hopkins rm. Sci Rep. 2015 Dec 16;5:18329. doi: 10.1038/srep18329. Sci Rep. 2015. PMID: 26671759 Free PMC article.
A platform for discovery of functional cell-penetrating peptides for efficient multi-cargo intracellular delivery.
Hoffmann K, Milech N, Juraja SM, Cunningham PT, Stone SR, Francis RW, Anastasas M, Hall CM, Heinrich T, Bogdawa HM, Winslow S, Scobie MN, Dewhurst RE, Florez L, Ong F, Kerfoot M, Champain D, Adams AM, Fletcher S, Viola HM, Hool LC, Connor T, Longville BAC, Tan YF, Kroeger K, Morath V, Weiss GA, Skerra A, Hopkins RM, Watt PM. Hoffmann K, et al. Among authors: hopkins rm. Sci Rep. 2018 Aug 22;8(1):12538. doi: 10.1038/s41598-018-30790-2. Sci Rep. 2018. PMID: 30135446 Free PMC article.
Poly-arginine and arginine-rich peptides are neuroprotective in stroke models.
Meloni BP, Brookes LM, Clark VW, Cross JL, Edwards AB, Anderton RS, Hopkins RM, Hoffmann K, Knuckey NW. Meloni BP, et al. Among authors: hopkins rm. J Cereb Blood Flow Metab. 2015 Jun;35(6):993-1004. doi: 10.1038/jcbfm.2015.11. Epub 2015 Feb 11. J Cereb Blood Flow Metab. 2015. PMID: 25669902 Free PMC article.
35 results