Horton B - Search Results

1

Mechanism of tumor rejection with doublets of CTLA-4, PD-1/PD-L1, or IDO blockade involves restored IL-2 production and proliferation of CD8(+) T cells directly within the tumor microenvironment.

Spranger S, Koblish HK, Horton B, Scherle PA, Newton R, Gajewski TF. Spranger S, et al. Among authors: horton b. J Immunother Cancer. 2014 Feb 18;2:3. doi: 10.1186/2051-1426-2-3. eCollection 2014. J Immunother Cancer. 2014. PMID: 24829760 Free PMC article.

2

The EGR2 targets LAG-3 and 4-1BB describe and regulate dysfunctional antigen-specific CD8+ T cells in the tumor microenvironment.

Williams JB, Horton BL, Zheng Y, Duan Y, Powell JD, Gajewski TF. Williams JB, et al. Among authors: horton bl. J Exp Med. 2017 Feb;214(2):381-400. doi: 10.1084/jem.20160485. Epub 2017 Jan 23. J Exp Med. 2017. PMID: 28115575 Free PMC article.

3

Tumor-Residing Batf3 Dendritic Cells Are Required for Effector T Cell Trafficking and Adoptive T Cell Therapy.

Spranger S, Dai D, Horton B, Gajewski TF. Spranger S, et al. Among authors: horton b. Cancer Cell. 2017 May 8;31(5):711-723.e4. doi: 10.1016/j.ccell.2017.04.003. Cancer Cell. 2017. PMID: 28486109 Free PMC article.

4

Intratumoral CD8⁺ T-cell Apoptosis Is a Major Component of T-cell Dysfunction and Impedes Antitumor Immunity.

Horton BL, Williams JB, Cabanov A, Spranger S, Gajewski TF. Horton BL, et al. Cancer Immunol Res. 2018 Jan;6(1):14-24. doi: 10.1158/2326-6066.CIR-17-0249. Epub 2017 Nov 2. Cancer Immunol Res. 2018. PMID: 29097422 Free PMC article.

5

Cancer Immunotherapy Targets Based on Understanding the T Cell-Inflamed Versus Non-T Cell-Inflamed Tumor Microenvironment.

Gajewski TF, Corrales L, Williams J, Horton B, Sivan A, Spranger S. Gajewski TF, et al. Among authors: horton b. Adv Exp Med Biol. 2017;1036:19-31. doi: 10.1007/978-3-319-67577-0_2. Adv Exp Med Biol. 2017. PMID: 29275462 Free PMC article. Review.

6

Back from the dead: TIL apoptosis in cancer immune evasion.

Horton BL, Gajewski TF. Horton BL, et al. Br J Cancer. 2018 Feb 6;118(3):309-311. doi: 10.1038/bjc.2017.483. Epub 2018 Jan 23. Br J Cancer. 2018. PMID: 29360810 Free PMC article. No abstract available.

7

A Tumor Cell-Intrinsic Yin-Yang Determining Immune Evasion.

Horton B, Spranger S. Horton B, et al. Immunity. 2018 Jul 17;49(1):11-13. doi: 10.1016/j.immuni.2018.07.001. Immunity. 2018. PMID: 30021140 Free PMC article.

8

Tissue Site and the Cancer Immunity Cycle.

Horton BL, Fessenden TB, Spranger S. Horton BL, et al. Trends Cancer. 2019 Oct;5(10):593-603. doi: 10.1016/j.trecan.2019.07.006. Epub 2019 Aug 13. Trends Cancer. 2019. PMID: 31706507 Free PMC article. Review.

9

CD36 - the Achilles' heel of T_reg cells.

Horton BL, Spranger S. Horton BL, et al. Nat Immunol. 2020 Mar;21(3):251-253. doi: 10.1038/s41590-020-0601-0. Nat Immunol. 2020. PMID: 32066948 No abstract available.

10

Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras.

Cohen MA, Zhang S, Sengupta S, Ma H, Bell GW, Horton B, Sharma B, George RE, Spranger S, Jaenisch R. Cohen MA, et al. Among authors: horton b. Cell Stem Cell. 2020 Apr 2;26(4):579-592.e6. doi: 10.1016/j.stem.2020.02.001. Epub 2020 Mar 5. Cell Stem Cell. 2020. PMID: 32142683 Free PMC article.

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