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Page 1
Genomic characterization of malignant progression in neoplastic pancreatic cysts.
Noë M, Niknafs N, Fischer CG, Hackeng WM, Beleva Guthrie V, Hosoda W, Debeljak M, Papp E, Adleff V, White JR, Luchini C, Pea A, Scarpa A, Butturini G, Zamboni G, Castelli P, Hong SM, Yachida S, Hiraoka N, Gill AJ, Samra JS, Offerhaus GJA, Hoorens A, Verheij J, Jansen C, Adsay NV, Jiang W, Winter J, Albores-Saavedra J, Terris B, Thompson ED, Roberts NJ, Hruban RH, Karchin R, Scharpf RB, Brosens LAA, Velculescu VE, Wood LD. Noë M, et al. Among authors: hosoda w. Nat Commun. 2020 Aug 14;11(1):4085. doi: 10.1038/s41467-020-17917-8. Nat Commun. 2020. PMID: 32796935 Free PMC article.
Aberrant Menin expression is an early event in pancreatic neuroendocrine tumorigenesis.
Hackeng WM, Brosens LA, Poruk KE, Noë M, Hosoda W, Poling JS, Rizzo A, Campbell-Thompson M, Atkinson MA, Konukiewitz B, Klöppel G, Heaphy CM, Meeker AK, Wood LD. Hackeng WM, et al. Among authors: hosoda w. Hum Pathol. 2016 Oct;56:93-100. doi: 10.1016/j.humpath.2016.06.006. Epub 2016 Jun 21. Hum Pathol. 2016. PMID: 27342911
Molecular Genetics of Pancreatic Neoplasms.
Hosoda W, Wood LD. Hosoda W, et al. Surg Pathol Clin. 2016 Dec;9(4):685-703. doi: 10.1016/j.path.2016.05.011. Epub 2016 Oct 12. Surg Pathol Clin. 2016. PMID: 27926367 Review.
Genetic analyses of isolated high-grade pancreatic intraepithelial neoplasia (HG-PanIN) reveal paucity of alterations in TP53 and SMAD4.
Hosoda W, Chianchiano P, Griffin JF, Pittman ME, Brosens LA, Noë M, Yu J, Shindo K, Suenaga M, Rezaee N, Yonescu R, Ning Y, Albores-Saavedra J, Yoshizawa N, Harada K, Yoshizawa A, Hanada K, Yonehara S, Shimizu M, Uehara T, Samra JS, Gill AJ, Wolfgang CL, Goggins MG, Hruban RH, Wood LD. Hosoda W, et al. J Pathol. 2017 May;242(1):16-23. doi: 10.1002/path.4884. Epub 2017 Mar 30. J Pathol. 2017. PMID: 28188630 Free PMC article.
IPMNs with co-occurring invasive cancers: neighbours but not always relatives.
Felsenstein M, Noë M, Masica DL, Hosoda W, Chianchiano P, Fischer CG, Lionheart G, Brosens LAA, Pea A, Yu J, Gemenetzis G, Groot VP, Makary MA, He J, Weiss MJ, Cameron JL, Wolfgang CL, Hruban RH, Roberts NJ, Karchin R, Goggins MG, Wood LD. Felsenstein M, et al. Among authors: hosoda w. Gut. 2018 Sep;67(9):1652-1662. doi: 10.1136/gutjnl-2017-315062. Epub 2018 Mar 2. Gut. 2018. PMID: 29500184 Free PMC article.
Single-cell sequencing defines genetic heterogeneity in pancreatic cancer precursor lesions.
Kuboki Y, Fischer CG, Beleva Guthrie V, Huang W, Yu J, Chianchiano P, Hosoda W, Zhang H, Zheng L, Shao X, Thompson ED, Waters K, Poling J, He J, Weiss MJ, Wolfgang CL, Goggins MG, Hruban RH, Roberts NJ, Karchin R, Wood LD. Kuboki Y, et al. Among authors: hosoda w. J Pathol. 2019 Mar;247(3):347-356. doi: 10.1002/path.5194. Epub 2019 Jan 16. J Pathol. 2019. PMID: 30430578 Free PMC article.
Intraductal Papillary Mucinous Neoplasms Arise From Multiple Independent Clones, Each With Distinct Mutations.
Fischer CG, Beleva Guthrie V, Braxton AM, Zheng L, Wang P, Song Q, Griffin JF, Chianchiano PE, Hosoda W, Niknafs N, Springer S, Dal Molin M, Masica D, Scharpf RB, Thompson ED, He J, Wolfgang CL, Hruban RH, Roberts NJ, Lennon AM, Jiao Y, Karchin R, Wood LD. Fischer CG, et al. Among authors: hosoda w. Gastroenterology. 2019 Oct;157(4):1123-1137.e22. doi: 10.1053/j.gastro.2019.06.001. Epub 2019 Jun 5. Gastroenterology. 2019. PMID: 31175866 Free PMC article.
Multiregion whole-exome sequencing of intraductal papillary mucinous neoplasms reveals frequent somatic KLF4 mutations predominantly in low-grade regions.
Fujikura K, Hosoda W, Felsenstein M, Song Q, Reiter JG, Zheng L, Beleva Guthrie V, Rincon N, Dal Molin M, Dudley J, Cohen JD, Wang P, Fischer CG, Braxton AM, Noë M, Jongepier M, Fernández-Del Castillo C, Mino-Kenudson M, Schmidt CM, Yip-Schneider MT, Lawlor RT, Salvia R, Roberts NJ, Thompson ED, Karchin R, Lennon AM, Jiao Y, Wood LD. Fujikura K, et al. Among authors: hosoda w. Gut. 2021 May;70(5):928-939. doi: 10.1136/gutjnl-2020-321217. Epub 2020 Oct 7. Gut. 2021. PMID: 33028669 Free PMC article.
85 results