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Intramuscular delivery of adenovirus serotype 5 vector expressing humanized protective antigen induces rapid protection against anthrax that may bypass intranasally originated preexisting adenovirus immunity.
Wu S, Zhang Z, Yu R, Zhang J, Liu Y, Song X, Yi S, Liu J, Chen J, Yin Y, Xu J, Hou L, Chen W. Wu S, et al. Among authors: hou l. Clin Vaccine Immunol. 2014 Feb;21(2):156-64. doi: 10.1128/CVI.00560-13. Epub 2013 Dec 4. Clin Vaccine Immunol. 2014. PMID: 24307239 Free PMC article.
Safety and immunogenicity of a recombinant adenovirus type-5 vector-based Ebola vaccine in healthy adults in Sierra Leone: a single-centre, randomised, double-blind, placebo-controlled, phase 2 trial.
Zhu FC, Wurie AH, Hou LH, Liang Q, Li YH, Russell JB, Wu SP, Li JX, Hu YM, Guo Q, Xu WB, Wurie AR, Wang WJ, Zhang Z, Yin WJ, Ghazzawi M, Zhang X, Duan L, Wang JZ, Chen W. Zhu FC, et al. Among authors: hou lh. Lancet. 2017 Feb 11;389(10069):621-628. doi: 10.1016/S0140-6736(16)32617-4. Epub 2016 Dec 23. Lancet. 2017. PMID: 28017399 Clinical Trial.
Immunization With a Novel Human Type 5 Adenovirus-Vectored Vaccine Expressing the Premembrane and Envelope Proteins of Zika Virus Provides Consistent and Sterilizing Protection in Multiple Immunocompetent and Immunocompromised Animal Models.
Guo Q, Chan JF, Poon VK, Wu S, Chan CC, Hou L, Yip CC, Ren C, Cai JP, Zhao M, Zhang AJ, Song X, Chan KH, Wang B, Kok KH, Wen Y, Yuen KY, Chen W. Guo Q, et al. Among authors: hou l. J Infect Dis. 2018 Jul 2;218(3):365-377. doi: 10.1093/infdis/jiy187. J Infect Dis. 2018. PMID: 29617816
5,967 results