Hoyles RK - Search Results

1

Inducible lineage-specific deletion of TbetaRII in fibroblasts defines a pivotal regulatory role during adult skin wound healing.

Denton CP, Khan K, Hoyles RK, Shiwen X, Leoni P, Chen Y, Eastwood M, Abraham DJ. Denton CP, et al. Among authors: hoyles rk. J Invest Dermatol. 2009 Jan;129(1):194-204. doi: 10.1038/jid.2008.171. Epub 2008 Jun 19. J Invest Dermatol. 2009. PMID: 18563179 Free article.

2

A multicenter, prospective, randomized, double-blind, placebo-controlled trial of corticosteroids and intravenous cyclophosphamide followed by oral azathioprine for the treatment of pulmonary fibrosis in scleroderma.

Hoyles RK, Ellis RW, Wellsbury J, Lees B, Newlands P, Goh NS, Roberts C, Desai S, Herrick AL, McHugh NJ, Foley NM, Pearson SB, Emery P, Veale DJ, Denton CP, Wells AU, Black CM, du Bois RM. Hoyles RK, et al. Arthritis Rheum. 2006 Dec;54(12):3962-70. doi: 10.1002/art.22204. Arthritis Rheum. 2006. PMID: 17133610 Free article. Clinical Trial.

3

Fibroblast-specific perturbation of transforming growth factor beta signaling provides insight into potential pathogenic mechanisms of scleroderma-associated lung fibrosis: exaggerated response to alveolar epithelial injury in a novel mouse model.

Hoyles RK, Khan K, Shiwen X, Howat SL, Lindahl GE, Leoni P, du Bois RM, Wells AU, Black CM, Abraham DJ, Denton CP. Hoyles RK, et al. Arthritis Rheum. 2008 Apr;58(4):1175-88. doi: 10.1002/art.23379. Arthritis Rheum. 2008. PMID: 18383385 Free article.

4

Pivotal role of connective tissue growth factor in lung fibrosis: MAPK-dependent transcriptional activation of type I collagen.

Ponticos M, Holmes AM, Shi-wen X, Leoni P, Khan K, Rajkumar VS, Hoyles RK, Bou-Gharios G, Black CM, Denton CP, Abraham DJ, Leask A, Lindahl GE. Ponticos M, et al. Among authors: hoyles rk. Arthritis Rheum. 2009 Jul;60(7):2142-55. doi: 10.1002/art.24620. Arthritis Rheum. 2009. PMID: 19565505 Free article.

5

An essential role for resident fibroblasts in experimental lung fibrosis is defined by lineage-specific deletion of high-affinity type II transforming growth factor β receptor.

Hoyles RK, Derrett-Smith EC, Khan K, Shiwen X, Howat SL, Wells AU, Abraham DJ, Denton CP. Hoyles RK, et al. Am J Respir Crit Care Med. 2011 Jan 15;183(2):249-61. doi: 10.1164/rccm.201002-0279OC. Epub 2010 Aug 13. Am J Respir Crit Care Med. 2011. PMID: 20709822

6

Increased epithelial permeability in pulmonary fibrosis in relation to disease progression.

Goh NS, Desai SR, Anagnostopoulos C, Hansell DM, Hoyles RK, Sato H, Denton CP, Black CM, du Bois RM, Wells AU. Goh NS, et al. Among authors: hoyles rk. Eur Respir J. 2011 Jul;38(1):184-90. doi: 10.1183/09031936.00010910. Epub 2010 Oct 28. Eur Respir J. 2011. PMID: 21030449 Free article.

7

Serum interleukin 6 is predictive of early functional decline and mortality in interstitial lung disease associated with systemic sclerosis.

De Lauretis A, Sestini P, Pantelidis P, Hoyles R, Hansell DM, Goh NS, Zappala CJ, Visca D, Maher TM, Denton CP, Ong VH, Abraham DJ, Kelleher P, Hector L, Wells AU, Renzoni EA. De Lauretis A, et al. J Rheumatol. 2013 Apr;40(4):435-46. doi: 10.3899/jrheum.120725. Epub 2013 Feb 1. J Rheumatol. 2013. PMID: 23378460

8

Short-Term Pulmonary Function Trends Are Predictive of Mortality in Interstitial Lung Disease Associated With Systemic Sclerosis.

Goh NS, Hoyles RK, Denton CP, Hansell DM, Renzoni EA, Maher TM, Nicholson AG, Wells AU. Goh NS, et al. Among authors: hoyles rk. Arthritis Rheumatol. 2017 Aug;69(8):1670-1678. doi: 10.1002/art.40130. Epub 2017 Jul 18. Arthritis Rheumatol. 2017. PMID: 28426895 Free article.

9

Serum markers of pulmonary epithelial damage in systemic sclerosis-associated interstitial lung disease and disease progression.

Stock CJW, Hoyles RK, Daccord C, Kokosi M, Visca D, De Lauretis A, Alfieri V, Kouranos V, Margaritopoulos G, George PM, Molyneaux PL, Chua F, Maher TM, Abraham DJ, Ong V, Donovan J, Sestini P, Denton CP, Wells AU, Renzoni EA. Stock CJW, et al. Among authors: hoyles rk. Respirology. 2021 May;26(5):461-468. doi: 10.1111/resp.13988. Epub 2020 Dec 17. Respirology. 2021. PMID: 33336433

10

The pan-PPAR agonist lanifibranor reduces development of lung fibrosis and attenuates cardiorespiratory manifestations in a transgenic mouse model of systemic sclerosis.

Derrett-Smith E, Clark KEN, Shiwen X, Abraham DJ, Hoyles RK, Lacombe O, Broqua P, Junien JL, Konstantinova I, Ong VH, Denton CP. Derrett-Smith E, et al. Among authors: hoyles rk. Arthritis Res Ther. 2021 Sep 6;23(1):234. doi: 10.1186/s13075-021-02592-x. Arthritis Res Ther. 2021. PMID: 34488870 Free PMC article.

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