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Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway.
Lee YR, Chen M, Lee JD, Zhang J, Lin SY, Fu TM, Chen H, Ishikawa T, Chiang SY, Katon J, Zhang Y, Shulga YV, Bester AC, Fung J, Monteleone E, Wan L, Shen C, Hsu CH, Papa A, Clohessy JG, Teruya-Feldstein J, Jain S, Wu H, Matesic L, Chen RH, Wei W, Pandolfi PP. Lee YR, et al. Among authors: hsu ch. Science. 2019 May 17;364(6441):eaau0159. doi: 10.1126/science.aau0159. Science. 2019. PMID: 31097636 Free PMC article.
PTEN Methylation by NSD2 Controls Cellular Sensitivity to DNA Damage.
Zhang J, Lee YR, Dang F, Gan W, Menon AV, Katon JM, Hsu CH, Asara JM, Tibarewal P, Leslie NR, Shi Y, Pandolfi PP, Wei W. Zhang J, et al. Among authors: hsu ch. Cancer Discov. 2019 Sep;9(9):1306-1323. doi: 10.1158/2159-8290.CD-18-0083. Epub 2019 Jun 19. Cancer Discov. 2019. PMID: 31217297 Free PMC article.
RNA m6A methylation regulates the ultraviolet-induced DNA damage response.
Xiang Y, Laurent B, Hsu CH, Nachtergaele S, Lu Z, Sheng W, Xu C, Chen H, Ouyang J, Wang S, Ling D, Hsu PH, Zou L, Jambhekar A, He C, Shi Y. Xiang Y, et al. Among authors: hsu ch, hsu ph. Nature. 2017 Mar 23;543(7646):573-576. doi: 10.1038/nature21671. Epub 2017 Mar 15. Nature. 2017. PMID: 28297716 Free PMC article.
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[No authors listed] [No authors listed] PMID: 34238760
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[No authors listed] [No authors listed] PMID: 35015681
m6A modification confers thermal vulnerability to HPV E7 oncotranscripts via reverse regulation of its reader protein IGF2BP1 upon heat stress.
Wang L, Zhan G, Maimaitiyiming Y, Su Y, Lin S, Liu J, Su K, Lin J, Shen S, He W, Wang F, Chen J, Sun S, Xue Y, Gu J, Chen X, Zhang J, Zhang L, Wang Q, Chang KJ, Chiou SH, Björklund M, Naranmandura H, Cheng X, Hsu CH. Wang L, et al. Among authors: hsu ch. Cell Rep. 2022 Oct 25;41(4):111546. doi: 10.1016/j.celrep.2022.111546. Cell Rep. 2022. PMID: 36288717 Free article.
2,308 results