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Second-generation shRNA libraries covering the mouse and human genomes.
Silva JM, Li MZ, Chang K, Ge W, Golding MC, Rickles RJ, Siolas D, Hu G, Paddison PJ, Schlabach MR, Sheth N, Bradshaw J, Burchard J, Kulkarni A, Cavet G, Sachidanandam R, McCombie WR, Cleary MA, Elledge SJ, Hannon GJ. Silva JM, et al. Among authors: hu g. Nat Genet. 2005 Nov;37(11):1281-8. doi: 10.1038/ng1650. Epub 2005 Oct 2. Nat Genet. 2005. PMID: 16200065
Cancer proliferation gene discovery through functional genomics.
Schlabach MR, Luo J, Solimini NL, Hu G, Xu Q, Li MZ, Zhao Z, Smogorzewska A, Sowa ME, Ang XL, Westbrook TF, Liang AC, Chang K, Hackett JA, Harper JW, Hannon GJ, Elledge SJ. Schlabach MR, et al. Among authors: hu g. Science. 2008 Feb 1;319(5863):620-4. doi: 10.1126/science.1149200. Science. 2008. PMID: 18239126 Free PMC article.
The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo.
Meerbrey KL, Hu G, Kessler JD, Roarty K, Li MZ, Fang JE, Herschkowitz JI, Burrows AE, Ciccia A, Sun T, Schmitt EM, Bernardi RJ, Fu X, Bland CS, Cooper TA, Schiff R, Rosen JM, Westbrook TF, Elledge SJ. Meerbrey KL, et al. Among authors: hu g. Proc Natl Acad Sci U S A. 2011 Mar 1;108(9):3665-70. doi: 10.1073/pnas.1019736108. Epub 2011 Feb 9. Proc Natl Acad Sci U S A. 2011. PMID: 21307310 Free PMC article.
Tyrosine phosphatase SHP2 promotes breast cancer progression and maintains tumor-initiating cells via activation of key transcription factors and a positive feedback signaling loop.
Aceto N, Sausgruber N, Brinkhaus H, Gaidatzis D, Martiny-Baron G, Mazzarol G, Confalonieri S, Quarto M, Hu G, Balwierz PJ, Pachkov M, Elledge SJ, van Nimwegen E, Stadler MB, Bentires-Alj M. Aceto N, et al. Among authors: hu g. Nat Med. 2012 Mar 4;18(4):529-37. doi: 10.1038/nm.2645. Nat Med. 2012. PMID: 22388088
A Serial shRNA Screen for Roadblocks to Reprogramming Identifies the Protein Modifier SUMO2.
Borkent M, Bennett BD, Lackford B, Bar-Nur O, Brumbaugh J, Wang L, Du Y, Fargo DC, Apostolou E, Cheloufi S, Maherali N, Elledge SJ, Hu G, Hochedlinger K. Borkent M, et al. Among authors: hu g. Stem Cell Reports. 2016 May 10;6(5):704-716. doi: 10.1016/j.stemcr.2016.02.004. Epub 2016 Mar 3. Stem Cell Reports. 2016. PMID: 26947976 Free PMC article.
8,130 results