Huang TT - Search Results

1

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes.

Rut W, Zmudzinski M, Snipas SJ, Bekes M, Huang TT, Drag M. Rut W, et al. Among authors: huang tt. Chem Sci. 2020 May 27;11(23):6058-6069. doi: 10.1039/d0sc01347a. eCollection 2020 Jun 21. Chem Sci. 2020. PMID: 32953009 Free PMC article.

2

The auto-generated fragment of the Usp1 deubiquitylase is a physiological substrate of the N-end rule pathway.

Piatkov KI, Colnaghi L, Békés M, Varshavsky A, Huang TT. Piatkov KI, et al. Among authors: huang tt. Mol Cell. 2012 Dec 28;48(6):926-33. doi: 10.1016/j.molcel.2012.10.012. Epub 2012 Nov 15. Mol Cell. 2012. PMID: 23159736 Free PMC article.

3

Deubiquitinases as a signaling target of oxidative stress.

Cotto-Rios XM, Békés M, Chapman J, Ueberheide B, Huang TT. Cotto-Rios XM, et al. Among authors: huang tt. Cell Rep. 2012 Dec 27;2(6):1475-84. doi: 10.1016/j.celrep.2012.11.011. Epub 2012 Dec 6. Cell Rep. 2012. PMID: 23219552 Free PMC article.

4

DUB-resistant ubiquitin to survey ubiquitination switches in mammalian cells.

Békés M, Okamoto K, Crist SB, Jones MJ, Chapman JR, Brasher BB, Melandri FD, Ueberheide BM, Denchi EL, Huang TT. Békés M, et al. Among authors: huang tt. Cell Rep. 2013 Nov 14;5(3):826-38. doi: 10.1016/j.celrep.2013.10.008. Epub 2013 Nov 7. Cell Rep. 2013. PMID: 24210823 Free PMC article.

5

SARS hCoV papain-like protease is a unique Lys48 linkage-specific di-distributive deubiquitinating enzyme.

Békés M, Rut W, Kasperkiewicz P, Mulder MP, Ovaa H, Drag M, Lima CD, Huang TT. Békés M, et al. Among authors: huang tt. Biochem J. 2015 Jun 1;468(2):215-26. doi: 10.1042/BJ20141170. Biochem J. 2015. PMID: 25764917 Free PMC article.

6

Recognition of Lys48-Linked Di-ubiquitin and Deubiquitinating Activities of the SARS Coronavirus Papain-like Protease.

Békés M, van der Heden van Noort GJ, Ekkebus R, Ovaa H, Huang TT, Lima CD. Békés M, et al. Among authors: huang tt. Mol Cell. 2016 May 19;62(4):572-85. doi: 10.1016/j.molcel.2016.04.016. Mol Cell. 2016. PMID: 27203180 Free PMC article.

7

SENP8 limits aberrant neddylation of NEDD8 pathway components to promote cullin-RING ubiquitin ligase function.

Coleman KE, Békés M, Chapman JR, Crist SB, Jones MJ, Ueberheide BM, Huang TT. Coleman KE, et al. Among authors: huang tt. Elife. 2017 May 5;6:e24325. doi: 10.7554/eLife.24325. Elife. 2017. PMID: 28475037 Free PMC article.

8

The COP9 signalosome inhibits Cullin-RING E3 ubiquitin ligases independently of its deneddylase activity.

Suisse A, Békés M, Huang TT, Treisman JE. Suisse A, et al. Among authors: huang tt. Fly (Austin). 2018;12(2):118-126. doi: 10.1080/19336934.2018.1429858. Epub 2018 Feb 9. Fly (Austin). 2018. PMID: 29355077 Free PMC article.

9

Activity profiling and structures of inhibitor-bound SARS-CoV-2-PLpro protease provides a framework for anti-COVID-19 drug design.

Rut W, Lv Z, Zmudzinski M, Patchett S, Nayak D, Snipas SJ, El Oualid F, Huang TT, Bekes M, Drag M, Olsen SK. Rut W, et al. Among authors: huang tt. bioRxiv [Preprint]. 2020 Apr 29:2020.04.29.068890. doi: 10.1101/2020.04.29.068890. bioRxiv. 2020. PMID: 32511411 Free PMC article. Updated. Preprint.

10

Activity profiling and crystal structures of inhibitor-bound SARS-CoV-2 papain-like protease: A framework for anti-COVID-19 drug design.

Rut W, Lv Z, Zmudzinski M, Patchett S, Nayak D, Snipas SJ, El Oualid F, Huang TT, Bekes M, Drag M, Olsen SK. Rut W, et al. Among authors: huang tt. Sci Adv. 2020 Oct 16;6(42):eabd4596. doi: 10.1126/sciadv.abd4596. Print 2020 Oct. Sci Adv. 2020. PMID: 33067239 Free PMC article.

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