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Comparing the novel method of assessing PrEP adherence/exposure using hair samples to other pharmacologic and traditional measures.
Baxi SM, Liu A, Bacchetti P, Mutua G, Sanders EJ, Kibengo FM, Haberer JE, Rooney J, Hendrix CW, Anderson PL, Huang Y, Priddy F, Gandhi M. Baxi SM, et al. Among authors: huang y. J Acquir Immune Defic Syndr. 2015 Jan 1;68(1):13-20. doi: 10.1097/QAI.0000000000000386. J Acquir Immune Defic Syndr. 2015. PMID: 25296098 Free PMC article. Clinical Trial.
Antiretroviral concentrations in small hair samples as a feasible marker of adherence in rural Kenya.
Hickey MD, Salmen CR, Tessler RA, Omollo D, Bacchetti P, Magerenge R, Mattah B, Salmen MR, Zoughbie D, Fiorella KJ, Geng E, Njoroge B, Jin C, Huang Y, Bukusi EA, Cohen CR, Gandhi M. Hickey MD, et al. Among authors: huang y. J Acquir Immune Defic Syndr. 2014 Jul 1;66(3):311-5. doi: 10.1097/QAI.0000000000000154. J Acquir Immune Defic Syndr. 2014. PMID: 24694932 Free PMC article.
Hair and plasma data show that lopinavir, ritonavir, and efavirenz all transfer from mother to infant in utero, but only efavirenz transfers via breastfeeding.
Gandhi M, Mwesigwa J, Aweeka F, Plenty A, Charlebois E, Ruel TD, Huang Y, Clark T, Ades V, Natureeba P, Luwedde FA, Achan J, Kamya MR, Havlir DV, Cohan D; Prevention of Malaria and HIV disease in Tororo (PROMOTE) study. Gandhi M, et al. Among authors: huang y. J Acquir Immune Defic Syndr. 2013 Aug 15;63(5):578-84. doi: 10.1097/QAI.0b013e31829c48ad. J Acquir Immune Defic Syndr. 2013. PMID: 24135775 Free PMC article. Clinical Trial.
Strong relationship between oral dose and tenofovir hair levels in a randomized trial: hair as a potential adherence measure for pre-exposure prophylaxis (PrEP).
Liu AY, Yang Q, Huang Y, Bacchetti P, Anderson PL, Jin C, Goggin K, Stojanovski K, Grant R, Buchbinder SP, Greenblatt RM, Gandhi M. Liu AY, et al. Among authors: huang y. PLoS One. 2014 Jan 8;9(1):e83736. doi: 10.1371/journal.pone.0083736. eCollection 2014. PLoS One. 2014. PMID: 24421901 Free PMC article. Clinical Trial.
Brief Report: Higher ART Adherence Is Associated With Lower Systemic Inflammation in Treatment-Naive Ugandans Who Achieve Virologic Suppression.
Castillo-Mancilla JR, Morrow M, Boum Y, Byakwaga H, Haberer JE, Martin JN, Bangsberg D, Mawhinney S, Musinguzi N, Huang Y, Tracy RP, Burdo TH, Williams K, Muzzora C, Hunt PW, Siedner MJ. Castillo-Mancilla JR, et al. Among authors: huang y. J Acquir Immune Defic Syndr. 2018 Apr 15;77(5):507-513. doi: 10.1097/QAI.0000000000001629. J Acquir Immune Defic Syndr. 2018. PMID: 29346185 Free PMC article.
Protease inhibitor levels in hair strongly predict virologic response to treatment.
Gandhi M, Ameli N, Bacchetti P, Gange SJ, Anastos K, Levine A, Hyman CL, Cohen M, Young M, Huang Y, Greenblatt RM; Women's Interagency HIV Study (WIHS). Gandhi M, et al. Among authors: huang y. AIDS. 2009 Feb 20;23(4):471-8. doi: 10.1097/QAD.0b013e328325a4a9. AIDS. 2009. PMID: 19165084 Free PMC article.
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