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Functional CD8+ but not CD4+ T cell responses develop independent of thymic epithelial MHC.
Martinic MM, van den Broek MF, Rülicke T, Huber C, Odermatt B, Reith W, Horvath E, Zellweger R, Fink K, Recher M, Eschli B, Hengartner H, Zinkernagel RM. Martinic MM, et al. Among authors: huber c. Proc Natl Acad Sci U S A. 2006 Sep 26;103(39):14435-40. doi: 10.1073/pnas.0606707103. Epub 2006 Sep 18. Proc Natl Acad Sci U S A. 2006. PMID: 16983067 Free PMC article.
PLD3 and PLD4 are single-stranded acid exonucleases that regulate endosomal nucleic-acid sensing.
Gavin AL, Huang D, Huber C, Mårtensson A, Tardif V, Skog PD, Blane TR, Thinnes TC, Osborn K, Chong HS, Kargaran F, Kimm P, Zeitjian A, Sielski RL, Briggs M, Schulz SR, Zarpellon A, Cravatt B, Pang ES, Teijaro J, de la Torre JC, O'Keeffe M, Hochrein H, Damme M, Teyton L, Lawson BR, Nemazee D. Gavin AL, et al. Among authors: huber c. Nat Immunol. 2018 Sep;19(9):942-953. doi: 10.1038/s41590-018-0179-y. Epub 2018 Aug 13. Nat Immunol. 2018. PMID: 30111894 Free PMC article.
A mutation of Ikbkg causes immune deficiency without impairing degradation of IkappaB alpha.
Siggs OM, Berger M, Krebs P, Arnold CN, Eidenschenk C, Huber C, Pirie E, Smart NG, Khovananth K, Xia Y, McInerney G, Karlsson Hedestam GB, Nemazee D, Beutler B. Siggs OM, et al. Among authors: huber c. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3046-51. doi: 10.1073/pnas.0915098107. Epub 2010 Jan 28. Proc Natl Acad Sci U S A. 2010. PMID: 20133626 Free PMC article.
1,814 results