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Compression of morbidity in a progeroid mouse model through the attenuation of myostatin/activin signalling.
Alyodawi K, Vermeij WP, Omairi S, Kretz O, Hopkinson M, Solagna F, Joch B, Brandt RMC, Barnhoorn S, van Vliet N, Ridwan Y, Essers J, Mitchell R, Morash T, Pasternack A, Ritvos O, Matsakas A, Collins-Hooper H, Huber TB, Hoeijmakers JHJ, Patel K. Alyodawi K, et al. Among authors: huber tb. J Cachexia Sarcopenia Muscle. 2019 Jun;10(3):662-686. doi: 10.1002/jcsm.12404. Epub 2019 Mar 27. J Cachexia Sarcopenia Muscle. 2019. PMID: 30916493 Free PMC article.
Microtubule Associated Protein 1b (MAP1B) Is a Marker of the Microtubular Cytoskeleton in Podocytes but Is Not Essential for the Function of the Kidney Filtration Barrier in Mice.
Gödel M, Temerinac D, Grahammer F, Hartleben B, Kretz O, Riederer BM, Propst F, Kohl S, Huber TB. Gödel M, et al. Among authors: huber tb. PLoS One. 2015 Oct 8;10(10):e0140116. doi: 10.1371/journal.pone.0140116. eCollection 2015. PLoS One. 2015. PMID: 26448484 Free PMC article.
Enhanced exercise and regenerative capacity in a mouse model that violates size constraints of oxidative muscle fibres.
Omairi S, Matsakas A, Degens H, Kretz O, Hansson KA, Solbrå AV, Bruusgaard JC, Joch B, Sartori R, Giallourou N, Mitchell R, Collins-Hooper H, Foster K, Pasternack A, Ritvos O, Sandri M, Narkar V, Swann JR, Huber TB, Patel K. Omairi S, et al. Among authors: huber tb. Elife. 2016 Aug 5;5:e16940. doi: 10.7554/eLife.16940. Elife. 2016. PMID: 27494364 Free PMC article.
YAP-mediated mechanotransduction determines the podocyte's response to damage.
Rinschen MM, Grahammer F, Hoppe AK, Kohli P, Hagmann H, Kretz O, Bertsch S, Höhne M, Göbel H, Bartram MP, Gandhirajan RK, Krüger M, Brinkkoetter PT, Huber TB, Kann M, Wickström SA, Benzing T, Schermer B. Rinschen MM, et al. Among authors: huber tb. Sci Signal. 2017 Apr 11;10(474):eaaf8165. doi: 10.1126/scisignal.aaf8165. Sci Signal. 2017. PMID: 28400537
The FERM protein EPB41L5 regulates actomyosin contractility and focal adhesion formation to maintain the kidney filtration barrier.
Schell C, Rogg M, Suhm M, Helmstädter M, Sellung D, Yasuda-Yamahara M, Kretz O, Küttner V, Suleiman H, Kollipara L, Zahedi RP, Sickmann A, Eimer S, Shaw AS, Kramer-Zucker A, Hirano-Kobayashi M, Abe T, Aizawa S, Grahammer F, Hartleben B, Dengjel J, Huber TB. Schell C, et al. Among authors: huber tb. Proc Natl Acad Sci U S A. 2017 Jun 6;114(23):E4621-E4630. doi: 10.1073/pnas.1617004114. Epub 2017 May 23. Proc Natl Acad Sci U S A. 2017. PMID: 28536193 Free PMC article.
Protein and Molecular Characterization of a Clinically Compliant Amniotic Fluid Stem Cell-Derived Extracellular Vesicle Fraction Capable of Accelerating Muscle Regeneration Through Enhancement of Angiogenesis.
Mellows B, Mitchell R, Antonioli M, Kretz O, Chambers D, Zeuner MT, Denecke B, Musante L, Ramachandra DL, Debacq-Chainiaux F, Holthofer H, Joch B, Ray S, Widera D, David AL, Huber TB, Dengjel J, De Coppi P, Patel K. Mellows B, et al. Among authors: huber tb. Stem Cells Dev. 2017 Sep 15;26(18):1316-1333. doi: 10.1089/scd.2017.0089. Epub 2017 Aug 22. Stem Cells Dev. 2017. PMID: 28679310
Secretome of adipose-derived mesenchymal stem cells promotes skeletal muscle regeneration through synergistic action of extracellular vesicle cargo and soluble proteins.
Mitchell R, Mellows B, Sheard J, Antonioli M, Kretz O, Chambers D, Zeuner MT, Tomkins JE, Denecke B, Musante L, Joch B, Debacq-Chainiaux F, Holthofer H, Ray S, Huber TB, Dengjel J, De Coppi P, Widera D, Patel K. Mitchell R, et al. Among authors: huber tb. Stem Cell Res Ther. 2019 Apr 5;10(1):116. doi: 10.1186/s13287-019-1213-1. Stem Cell Res Ther. 2019. PMID: 30953537 Free PMC article.
309 results