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NF1 mutation drives neuronal activity-dependent initiation of optic glioma.
Pan Y, Hysinger JD, Barron T, Schindler NF, Cobb O, Guo X, Yalçın B, Anastasaki C, Mulinyawe SB, Ponnuswami A, Scheaffer S, Ma Y, Chang KC, Xia X, Toonen JA, Lennon JJ, Gibson EM, Huguenard JR, Liau LM, Goldberg JL, Monje M, Gutmann DH. Pan Y, et al. Among authors: huguenard jr. Nature. 2021 Jun;594(7862):277-282. doi: 10.1038/s41586-021-03580-6. Epub 2021 May 26. Nature. 2021. PMID: 34040258 Free PMC article.
Reliability of human cortical organoid generation.
Yoon SJ, Elahi LS, Pașca AM, Marton RM, Gordon A, Revah O, Miura Y, Walczak EM, Holdgate GM, Fan HC, Huguenard JR, Geschwind DH, Pașca SP. Yoon SJ, et al. Among authors: huguenard jr. Nat Methods. 2019 Jan;16(1):75-78. doi: 10.1038/s41592-018-0255-0. Epub 2018 Dec 20. Nat Methods. 2019. PMID: 30573846 Free PMC article.
Neuronal defects in a human cellular model of 22q11.2 deletion syndrome.
Khan TA, Revah O, Gordon A, Yoon SJ, Krawisz AK, Goold C, Sun Y, Kim CH, Tian Y, Li MY, Schaepe JM, Ikeda K, Amin ND, Sakai N, Yazawa M, Kushan L, Nishino S, Porteus MH, Rapoport JL, Bernstein JA, O'Hara R, Bearden CE, Hallmayer JF, Huguenard JR, Geschwind DH, Dolmetsch RE, Paşca SP. Khan TA, et al. Among authors: huguenard jr. Nat Med. 2020 Dec;26(12):1888-1898. doi: 10.1038/s41591-020-1043-9. Epub 2020 Sep 28. Nat Med. 2020. PMID: 32989314 Free PMC article.
Maladaptive myelination promotes generalized epilepsy progression.
Knowles JK, Xu H, Soane C, Batra A, Saucedo T, Frost E, Tam LT, Fraga D, Ni L, Villar K, Talmi S, Huguenard JR, Monje M. Knowles JK, et al. Among authors: huguenard jr. Nat Neurosci. 2022 May;25(5):596-606. doi: 10.1038/s41593-022-01052-2. Epub 2022 May 2. Nat Neurosci. 2022. PMID: 35501379 Free PMC article.
Maturation and circuit integration of transplanted human cortical organoids.
Revah O, Gore F, Kelley KW, Andersen J, Sakai N, Chen X, Li MY, Birey F, Yang X, Saw NL, Baker SW, Amin ND, Kulkarni S, Mudipalli R, Cui B, Nishino S, Grant GA, Knowles JK, Shamloo M, Huguenard JR, Deisseroth K, Pașca SP. Revah O, et al. Among authors: huguenard jr. Nature. 2022 Oct;610(7931):319-326. doi: 10.1038/s41586-022-05277-w. Epub 2022 Oct 12. Nature. 2022. PMID: 36224417 Free PMC article.
Who let the spikes out?
Dulla CG, Huguenard JR. Dulla CG, et al. Among authors: huguenard jr. Nat Neurosci. 2009 Aug;12(8):959-60. doi: 10.1038/nn0809-959. Nat Neurosci. 2009. PMID: 19636347 Free PMC article. No abstract available.
Neocortical excitation/inhibition balance in information processing and social dysfunction.
Yizhar O, Fenno LE, Prigge M, Schneider F, Davidson TJ, O'Shea DJ, Sohal VS, Goshen I, Finkelstein J, Paz JT, Stehfest K, Fudim R, Ramakrishnan C, Huguenard JR, Hegemann P, Deisseroth K. Yizhar O, et al. Among authors: huguenard jr. Nature. 2011 Jul 27;477(7363):171-8. doi: 10.1038/nature10360. Nature. 2011. PMID: 21796121 Free PMC article.
A call for transparent reporting to optimize the predictive value of preclinical research.
Landis SC, Amara SG, Asadullah K, Austin CP, Blumenstein R, Bradley EW, Crystal RG, Darnell RB, Ferrante RJ, Fillit H, Finkelstein R, Fisher M, Gendelman HE, Golub RM, Goudreau JL, Gross RA, Gubitz AK, Hesterlee SE, Howells DW, Huguenard J, Kelner K, Koroshetz W, Krainc D, Lazic SE, Levine MS, Macleod MR, McCall JM, Moxley RT 3rd, Narasimhan K, Noble LJ, Perrin S, Porter JD, Steward O, Unger E, Utz U, Silberberg SD. Landis SC, et al. Nature. 2012 Oct 11;490(7419):187-91. doi: 10.1038/nature11556. Nature. 2012. PMID: 23060188 Free PMC article.
197 results