Humeau LM - Search Results

1

Efficient lentiviral vector-mediated control of HIV-1 replication in CD4 lymphocytes from diverse HIV+ infected patients grouped according to CD4 count and viral load.

Humeau LM, Binder GK, Lu X, Slepushkin V, Merling R, Echeagaray P, Pereira M, Slepushkina T, Barnett S, Dropulic LK, Carroll R, Levine BL, June CH, Dropulic B. Humeau LM, et al. Mol Ther. 2004 Jun;9(6):902-13. doi: 10.1016/j.ymthe.2004.03.005. Mol Ther. 2004. PMID: 15194057 Free article.

2

Regulatory considerations for novel gene therapy products: a review of the process leading to the first clinical lentiviral vector.

Manilla P, Rebello T, Afable C, Lu X, Slepushkin V, Humeau LM, Schonely K, Ni Y, Binder GK, Levine BL, MacGregor RR, June CH, Dropulic B. Manilla P, et al. Among authors: humeau lm. Hum Gene Ther. 2005 Jan;16(1):17-25. doi: 10.1089/hum.2005.16.17. Hum Gene Ther. 2005. PMID: 15703485 Review.

3

In vivo selection for human and murine hematopoietic cells transduced with a therapeutic MGMT lentiviral vector that inhibits HIV replication.

Davis BM, Humeau L, Dropulic B. Davis BM, et al. Mol Ther. 2004 Feb;9(2):160-72. doi: 10.1016/j.ymthe.2003.11.003. Mol Ther. 2004. PMID: 14759800 Free article.

4

Safe two-plasmid production for the first clinical lentivirus vector that achieves >99% transduction in primary cells using a one-step protocol.

Lu X, Humeau L, Slepushkin V, Binder G, Yu Q, Slepushkina T, Chen Z, Merling R, Davis B, Chang YN, Dropulic B. Lu X, et al. J Gene Med. 2004 Sep;6(9):963-73. doi: 10.1002/jgm.593. J Gene Med. 2004. PMID: 15352069

5

Generation of a packaging cell line for prolonged large-scale production of high-titer HIV-1-based lentiviral vector.

Ni Y, Sun S, Oparaocha I, Humeau L, Davis B, Cohen R, Binder G, Chang YN, Slepushkin V, Dropulic B. Ni Y, et al. J Gene Med. 2005 Jun;7(6):818-34. doi: 10.1002/jgm.726. J Gene Med. 2005. PMID: 15693055

6

Inhibition of simian/human immunodeficiency virus replication in CD4+ T cells derived from lentiviral-transduced CD34+ hematopoietic cells.

Braun SE, Wong FE, Connole M, Qiu G, Lee L, Gillis J, Lu X, Humeau L, Slepushkin V, Binder GK, Dropulic B, Johnson RP. Braun SE, et al. Mol Ther. 2005 Dec;12(6):1157-67. doi: 10.1016/j.ymthe.2005.07.698. Epub 2005 Sep 15. Mol Ther. 2005. PMID: 16168713 Free article.

7

Gene transfer in humans using a conditionally replicating lentiviral vector.

Levine BL, Humeau LM, Boyer J, MacGregor RR, Rebello T, Lu X, Binder GK, Slepushkin V, Lemiale F, Mascola JR, Bushman FD, Dropulic B, June CH. Levine BL, et al. Among authors: humeau lm. Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17372-7. doi: 10.1073/pnas.0608138103. Epub 2006 Nov 7. Proc Natl Acad Sci U S A. 2006. PMID: 17090675 Free PMC article.

8

Potent inhibition of simian immunodeficiency virus (SIV) replication by an SIV-based lentiviral vector expressing antisense Env.

Braun SE, Lu XV, Wong FE, Connole M, Qiu G, Chen Z, Slepushkina T, Slepushkin V, Humeau LM, Dropulic B, Johnson RP. Braun SE, et al. Among authors: humeau lm. Hum Gene Ther. 2007 Jul;18(7):653-64. doi: 10.1089/hum.2007.003. Hum Gene Ther. 2007. PMID: 17600461

9

Patient monitoring and follow-up in lentiviral clinical trials.

McGarrity GJ, Hoyah G, Winemiller A, Andre K, Stein D, Blick G, Greenberg RN, Kinder C, Zolopa A, Binder-Scholl G, Tebas P, June CH, Humeau LM, Rebello T. McGarrity GJ, et al. Among authors: humeau lm. J Gene Med. 2013 Feb;15(2):78-82. doi: 10.1002/jgm.2691. J Gene Med. 2013. PMID: 23322669

10

ABC transporter inhibitors that are substrates enhance lentiviral vector transduction into primitive hematopoietic progenitor cells.

Davis BM, Humeau L, Slepushkin V, Binder G, Korshalla L, Ni Y, Ogunjimi EO, Chang LF, Lu X, Dropulic B. Davis BM, et al. Blood. 2004 Jul 15;104(2):364-73. doi: 10.1182/blood-2003-07-2363. Epub 2004 Apr 1. Blood. 2004. PMID: 15059841 Free article.

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