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Examining the utility of extended laboratory panel testing in the emergency department for risk stratification of patients with COVID-19: a single-centre retrospective service evaluation.
Ponsford MJ, Burton RJ, Smith L, Khan PY, Andrews R, Cuff S, Tan L, Eberl M, Humphreys IR, Babolhavaeji F, Artemiou A, Pandey M, Jolles SRA, Underwood J. Ponsford MJ, et al. Among authors: humphreys ir. J Clin Pathol. 2022 Apr;75(4):255-262. doi: 10.1136/jclinpath-2020-207157. Epub 2021 Feb 19. J Clin Pathol. 2022. PMID: 33608408 Free PMC article.
CD200 receptor restriction of myeloid cell responses antagonizes antiviral immunity and facilitates cytomegalovirus persistence within mucosal tissue.
Stack G, Jones E, Marsden M, Stacey MA, Snelgrove RJ, Lacaze P, Jacques LC, Cuff SM, Stanton RJ, Gallimore AM, Hussell T, Wilkinson GW, Ghazal P, Taylor PR, Humphreys IR. Stack G, et al. Among authors: humphreys ir. PLoS Pathog. 2015 Feb 5;11(2):e1004641. doi: 10.1371/journal.ppat.1004641. eCollection 2015 Feb. PLoS Pathog. 2015. PMID: 25654642 Free PMC article.
The protective effect of inflammatory monocytes during systemic C. albicans infection is dependent on collaboration between C-type lectin-like receptors.
Thompson A, Davies LC, Liao CT, da Fonseca DM, Griffiths JS, Andrews R, Jones AV, Clement M, Brown GD, Humphreys IR, Taylor PR, Orr SJ. Thompson A, et al. Among authors: humphreys ir. PLoS Pathog. 2019 Jun 26;15(6):e1007850. doi: 10.1371/journal.ppat.1007850. eCollection 2019 Jun. PLoS Pathog. 2019. PMID: 31242262 Free PMC article.
Burden of nosocomial COVID-19 in Wales: results from a multicentre retrospective observational study of 2508 hospitalised adults.
Ponsford MJ, Jefferies R, Davies C, Farewell D, Humphreys IR, Jolles S, Fairbairn S, Lewis K, Menzies D, Benjamin A, Thaivalappil F, Williams C, Barry SM. Ponsford MJ, et al. Among authors: humphreys ir. Thorax. 2021 Dec;76(12):1246-1249. doi: 10.1136/thoraxjnl-2021-216964. Epub 2021 Jul 22. Thorax. 2021. PMID: 34301738 Free PMC article.
A Systematic Review and Meta-Analysis of Inpatient Mortality Associated With Nosocomial and Community COVID-19 Exposes the Vulnerability of Immunosuppressed Adults.
Ponsford MJ, Ward TJC, Stoneham SM, Dallimore CM, Sham D, Osman K, Barry SM, Jolles S, Humphreys IR, Farewell D. Ponsford MJ, et al. Among authors: humphreys ir. Front Immunol. 2021 Oct 6;12:744696. doi: 10.3389/fimmu.2021.744696. eCollection 2021. Front Immunol. 2021. PMID: 34691049 Free PMC article.
An Analysis of Serological Response and Infection Outcomes Following Oxford-AstraZeneca (AZD1222) and Pfizer-BioNTech (mRNA BNT162b2) SARS-CoV-2 Vaccines in Kidney and Kidney-pancreas Transplants.
Asderakis A, Khalid U, Koimtzis G, Ponsford MJ, Szabo L, Chalklin C, Bramhall K, Grant L, Moat SJ, Humphreys IR, Jolles SR. Asderakis A, et al. Among authors: humphreys ir. Transplantation. 2022 Jul 1;106(7):1421-1429. doi: 10.1097/TP.0000000000004105. Epub 2022 Mar 8. Transplantation. 2022. PMID: 35283457 Free PMC article.
SARS-CoV-2 host-shutoff impacts innate NK cell functions, but antibody-dependent NK activity is strongly activated through non-spike antibodies.
Fielding CA, Sabberwal P, Williamson JC, Greenwood EJD, Crozier TWM, Zelek W, Seow J, Graham C, Huettner I, Edgeworth JD, Price DA, Morgan PB, Ladell K, Eberl M, Humphreys IR, Merrick B, Doores K, Wilson SJ, Lehner PJ, Wang ECY, Stanton RJ. Fielding CA, et al. Among authors: humphreys ir. Elife. 2022 May 19;11:e74489. doi: 10.7554/eLife.74489. Elife. 2022. PMID: 35587364 Free PMC article.
91 results