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A mechanism-inspired UDP-N-acetylglucosamine pyrophosphorylase inhibitor.
Raimi OG, Hurtado-Guerrero R, Borodkin V, Ferenbach A, Urbaniak MD, Ferguson MAJ, van Aalten DMF. Raimi OG, et al. RSC Chem Biol. 2020 Mar 24;1(1):13-25. doi: 10.1039/c9cb00017h. eCollection 2020 Apr 16. RSC Chem Biol. 2020. PMID: 34458745 Free PMC article.
Molecular mechanisms of O-GlcNAcylation.
Hurtado-Guerrero R, Dorfmueller HC, van Aalten DM. Hurtado-Guerrero R, et al. Curr Opin Struct Biol. 2008 Oct;18(5):551-7. doi: 10.1016/j.sbi.2008.09.005. Epub 2008 Oct 6. Curr Opin Struct Biol. 2008. PMID: 18822376 Review.
Natural product-guided discovery of a fungal chitinase inhibitor.
Rush CL, Schüttelkopf AW, Hurtado-Guerrero R, Blair DE, Ibrahim AF, Desvergnes S, Eggleston IM, van Aalten DM. Rush CL, et al. Chem Biol. 2010 Dec 22;17(12):1275-81. doi: 10.1016/j.chembiol.2010.07.018. Chem Biol. 2010. PMID: 21168763 Free PMC article.
112 results