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Engagement of Nuclear Coactivator 7 by 3-Hydroxyanthranilic Acid Enhances Activation of Aryl Hydrocarbon Receptor in Immunoregulatory Dendritic Cells.
Gargaro M, Vacca C, Massari S, Scalisi G, Manni G, Mondanelli G, Mazza EMC, Bicciato S, Pallotta MT, Orabona C, Belladonna ML, Volpi C, Bianchi R, Matino D, Iacono A, Panfili E, Proietti E, Iamandii IM, Cecchetti V, Puccetti P, Tabarrini O, Fallarino F, Grohmann U. Gargaro M, et al. Among authors: iacono a. Front Immunol. 2019 Aug 20;10:1973. doi: 10.3389/fimmu.2019.01973. eCollection 2019. Front Immunol. 2019. PMID: 31481962 Free PMC article.
Allosteric modulation of metabotropic glutamate receptor 4 activates IDO1-dependent, immunoregulatory signaling in dendritic cells.
Volpi C, Mondanelli G, Pallotta MT, Vacca C, Iacono A, Gargaro M, Albini E, Bianchi R, Belladonna ML, Celanire S, Mordant C, Heroux M, Royer-Urios I, Schneider M, Vitte PA, Cacquevel M, Galibert L, Poli SM, Solari A, Bicciato S, Calvitti M, Antognelli C, Puccetti P, Orabona C, Fallarino F, Grohmann U. Volpi C, et al. Among authors: iacono a. Neuropharmacology. 2016 Mar;102:59-71. doi: 10.1016/j.neuropharm.2015.10.036. Epub 2015 Oct 30. Neuropharmacology. 2016. PMID: 26522434 Free PMC article.
A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells.
Mondanelli G, Bianchi R, Pallotta MT, Orabona C, Albini E, Iacono A, Belladonna ML, Vacca C, Fallarino F, Macchiarulo A, Ugel S, Bronte V, Gevi F, Zolla L, Verhaar A, Peppelenbosch M, Mazza EMC, Bicciato S, Laouar Y, Santambrogio L, Puccetti P, Volpi C, Grohmann U. Mondanelli G, et al. Among authors: iacono a. Immunity. 2017 Feb 21;46(2):233-244. doi: 10.1016/j.immuni.2017.01.005. Epub 2017 Feb 14. Immunity. 2017. PMID: 28214225 Free PMC article.
Amino-acid sensing and degrading pathways in immune regulation.
Grohmann U, Mondanelli G, Belladonna ML, Orabona C, Pallotta MT, Iacono A, Puccetti P, Volpi C. Grohmann U, et al. Among authors: iacono a. Cytokine Growth Factor Rev. 2017 Jun;35:37-45. doi: 10.1016/j.cytogfr.2017.05.004. Epub 2017 May 18. Cytokine Growth Factor Rev. 2017. PMID: 28545736 Free article. Review.
Deficiency of immunoregulatory indoleamine 2,3-dioxygenase 1in juvenile diabetes.
Orabona C, Mondanelli G, Pallotta MT, Carvalho A, Albini E, Fallarino F, Vacca C, Volpi C, Belladonna ML, Berioli MG, Ceccarini G, Esposito SM, Scattoni R, Verrotti A, Ferretti A, De Giorgi G, Toni S, Cappa M, Matteoli MC, Bianchi R, Matino D, Iacono A, Puccetti M, Cunha C, Bicciato S, Antognelli C, Talesa VN, Chatenoud L, Fuchs D, Pilotte L, Van den Eynde B, Lemos MC, Romani L, Puccetti P, Grohmann U. Orabona C, et al. Among authors: iacono a. JCI Insight. 2018 Mar 22;3(6):e96244. doi: 10.1172/jci.insight.96244. JCI Insight. 2018. PMID: 29563329 Free PMC article.
Amino acid metabolism as drug target in autoimmune diseases.
Mondanelli G, Iacono A, Carvalho A, Orabona C, Volpi C, Pallotta MT, Matino D, Esposito S, Grohmann U. Mondanelli G, et al. Among authors: iacono a. Autoimmun Rev. 2019 Apr;18(4):334-348. doi: 10.1016/j.autrev.2019.02.004. Epub 2019 Feb 22. Autoimmun Rev. 2019. PMID: 30797943 Free article. Review.
Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation.
Mondanelli G, Coletti A, Greco FA, Pallotta MT, Orabona C, Iacono A, Belladonna ML, Albini E, Panfili E, Fallarino F, Gargaro M, Manni G, Matino D, Carvalho A, Cunha C, Maciel P, Di Filippo M, Gaetani L, Bianchi R, Vacca C, Iamandii IM, Proietti E, Boscia F, Annunziato L, Peppelenbosch M, Puccetti P, Calabresi P, Macchiarulo A, Santambrogio L, Volpi C, Grohmann U. Mondanelli G, et al. Among authors: iacono a. Proc Natl Acad Sci U S A. 2020 Feb 18;117(7):3848-3857. doi: 10.1073/pnas.1918215117. Epub 2020 Feb 5. Proc Natl Acad Sci U S A. 2020. PMID: 32024760 Free PMC article.
Class IA PI3Ks regulate subcellular and functional dynamics of IDO1.
Iacono A, Pompa A, De Marchis F, Panfili E, Greco FA, Coletti A, Orabona C, Volpi C, Belladonna ML, Mondanelli G, Albini E, Vacca C, Gargaro M, Fallarino F, Bianchi R, De Marcos Lousa C, Mazza EM, Bicciato S, Proietti E, Milano F, Martelli MP, Iamandii IM, Graupera Garcia-Mila M, Llena Sopena J, Hawkins P, Suire S, Okkenhaug K, Stark AK, Grassi F, Bellucci M, Puccetti P, Santambrogio L, Macchiarulo A, Grohmann U, Pallotta MT. Iacono A, et al. EMBO Rep. 2020 Dec 3;21(12):e49756. doi: 10.15252/embr.201949756. Epub 2020 Nov 7. EMBO Rep. 2020. PMID: 33159421 Free PMC article.
337 results