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Obesity and hyperinsulinemia drive adipocytes to activate a cell cycle program and senesce.
Nat Med. 2021 Nov;27(11):1941-1953. doi: 10.1038/s41591-021-01501-8. Epub 2021 Oct 4.
Nat Med. 2021.
PMID: 34608330
The transcription factor Foxp1 regulates aerobic glycolysis in adipocytes and myocytes.
Ma H, Sukonina V, Zhang W, Meng F, Subhash S, Palmgren H, Alexandersson I, Han H, Zhou S, Bartesaghi S, Kanduri C, Enerbäck S.
Ma H, et al. Among authors: alexandersson i.
J Biol Chem. 2023 Jun;299(6):104795. doi: 10.1016/j.jbc.2023.104795. Epub 2023 May 5.
J Biol Chem. 2023.
PMID: 37150320
Free PMC article.
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Cellular senescence in hepatocytes contributes to metabolic disturbances in NASH.
Bonnet L, Alexandersson I, Baboota RK, Kroon T, Oscarsson J, Smith U, Boucher J.
Bonnet L, et al. Among authors: alexandersson i.
Front Endocrinol (Lausanne). 2022 Aug 22;13:957616. doi: 10.3389/fendo.2022.957616. eCollection 2022.
Front Endocrinol (Lausanne). 2022.
PMID: 36072934
Free PMC article.
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Chronotherapy with a glucokinase activator profoundly improves metabolism in obese Zucker rats.
Kroon T, Hagstedt T, Alexandersson I, Ferm A, Petersson M, Maurer S, Zarrouki B, Wallenius K, Oakes ND, Boucher J.
Kroon T, et al. Among authors: alexandersson i.
Sci Transl Med. 2022 Oct 26;14(668):eabh1316. doi: 10.1126/scitranslmed.abh1316. Epub 2022 Oct 26.
Sci Transl Med. 2022.
PMID: 36288279
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PPARγ and PPARα synergize to induce robust browning of white fat in vivo.
Kroon T, Harms M, Maurer S, Bonnet L, Alexandersson I, Lindblom A, Ahnmark A, Nilsson D, Gennemark P, O'Mahony G, Osinski V, McNamara C, Boucher J.
Kroon T, et al. Among authors: alexandersson i.
Mol Metab. 2020 Jun;36:100964. doi: 10.1016/j.molmet.2020.02.007. Epub 2020 Feb 18.
Mol Metab. 2020.
PMID: 32248079
Free PMC article.
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Mature Human White Adipocytes Cultured under Membranes Maintain Identity, Function, and Can Transdifferentiate into Brown-like Adipocytes.
Harms MJ, Li Q, Lee S, Zhang C, Kull B, Hallen S, Thorell A, Alexandersson I, Hagberg CE, Peng XR, Mardinoglu A, Spalding KL, Boucher J.
Harms MJ, et al. Among authors: alexandersson i.
Cell Rep. 2019 Apr 2;27(1):213-225.e5. doi: 10.1016/j.celrep.2019.03.026.
Cell Rep. 2019.
PMID: 30943403
Free article.
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Isolation and Culture of Human Mature Adipocytes Using Membrane Mature Adipocyte Aggregate Cultures (MAAC).
Alexandersson I, Harms MJ, Boucher J.
Alexandersson I, et al.
J Vis Exp. 2020 Feb 13;(156). doi: 10.3791/60485.
J Vis Exp. 2020.
PMID: 32116300
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