Ikeda JE - Search Results

1

Mice deficient in the Rab5 guanine nucleotide exchange factor ALS2/alsin exhibit age-dependent neurological deficits and altered endosome trafficking.

Hadano S, Benn SC, Kakuta S, Otomo A, Sudo K, Kunita R, Suzuki-Utsunomiya K, Mizumura H, Shefner JM, Cox GA, Iwakura Y, Brown RH Jr, Ikeda JE. Hadano S, et al. Among authors: ikeda je. Hum Mol Genet. 2006 Jan 15;15(2):233-50. doi: 10.1093/hmg/ddi440. Epub 2005 Dec 1. Hum Mol Genet. 2006. PMID: 16321985

2

ALS2CL, a novel ALS2-interactor, modulates ALS2-mediated endosome dynamics.

Suzuki-Utsunomiya K, Hadano S, Otomo A, Kunita R, Mizumura H, Osuga H, Ikeda JE. Suzuki-Utsunomiya K, et al. Among authors: ikeda je. Biochem Biophys Res Commun. 2007 Mar 9;354(2):491-7. doi: 10.1016/j.bbrc.2006.12.229. Epub 2007 Jan 11. Biochem Biophys Res Commun. 2007. PMID: 17239822

3

The Rab5 activator ALS2/alsin acts as a novel Rac1 effector through Rac1-activated endocytosis.

Kunita R, Otomo A, Mizumura H, Suzuki-Utsunomiya K, Hadano S, Ikeda JE. Kunita R, et al. Among authors: ikeda je. J Biol Chem. 2007 Jun 1;282(22):16599-611. doi: 10.1074/jbc.M610682200. Epub 2007 Apr 4. J Biol Chem. 2007. PMID: 17409386 Free article.

4

Molecular and cellular function of ALS2/alsin: implication of membrane dynamics in neuronal development and degeneration.

Hadano S, Kunita R, Otomo A, Suzuki-Utsunomiya K, Ikeda JE. Hadano S, et al. Among authors: ikeda je. Neurochem Int. 2007 Jul-Sep;51(2-4):74-84. doi: 10.1016/j.neuint.2007.04.010. Epub 2007 May 4. Neurochem Int. 2007. PMID: 17566607 Review.

5

ALS2/alsin deficiency in neurons leads to mild defects in macropinocytosis and axonal growth.

Otomo A, Kunita R, Suzuki-Utsunomiya K, Mizumura H, Onoe K, Osuga H, Hadano S, Ikeda JE. Otomo A, et al. Among authors: ikeda je. Biochem Biophys Res Commun. 2008 May 23;370(1):87-92. doi: 10.1016/j.bbrc.2008.01.177. Epub 2008 Mar 19. Biochem Biophys Res Commun. 2008. PMID: 18358238

6

Loss of ALS2/Alsin exacerbates motor dysfunction in a SOD1-expressing mouse ALS model by disturbing endolysosomal trafficking.

Hadano S, Otomo A, Kunita R, Suzuki-Utsunomiya K, Akatsuka A, Koike M, Aoki M, Uchiyama Y, Itoyama Y, Ikeda JE. Hadano S, et al. Among authors: ikeda je. PLoS One. 2010 Mar 22;5(3):e9805. doi: 10.1371/journal.pone.0009805. PLoS One. 2010. PMID: 20339559 Free PMC article.

7

Genetic background and gender effects on gross phenotypes in congenic lines of ALS2/alsin-deficient mice.

Hadano S, Yoshii Y, Otomo A, Kunita R, Suzuki-Utsunomiya K, Pan L, Kakuta S, Iwasaki Y, Iwakura Y, Ikeda JE. Hadano S, et al. Among authors: ikeda je. Neurosci Res. 2010 Oct;68(2):131-6. doi: 10.1016/j.neures.2010.06.004. Epub 2010 Jun 14. Neurosci Res. 2010. PMID: 20558214

8

Defective relocalization of ALS2/alsin missense mutants to Rac1-induced macropinosomes accounts for loss of their cellular function and leads to disturbed amphisome formation.

Otomo A, Kunita R, Suzuki-Utsunomiya K, Ikeda JE, Hadano S. Otomo A, et al. Among authors: ikeda je. FEBS Lett. 2011 Mar 9;585(5):730-6. doi: 10.1016/j.febslet.2011.01.045. Epub 2011 Feb 17. FEBS Lett. 2011. PMID: 21300063 Free article.

9

ALS2, a novel guanine nucleotide exchange factor for the small GTPase Rab5, is implicated in endosomal dynamics.

Otomo A, Hadano S, Okada T, Mizumura H, Kunita R, Nishijima H, Showguchi-Miyata J, Yanagisawa Y, Kohiki E, Suga E, Yasuda M, Osuga H, Nishimoto T, Narumiya S, Ikeda JE. Otomo A, et al. Among authors: ikeda je. Hum Mol Genet. 2003 Jul 15;12(14):1671-87. doi: 10.1093/hmg/ddg184. Hum Mol Genet. 2003. PMID: 12837691

10

Homo-oligomerization of ALS2 through its unique carboxyl-terminal regions is essential for the ALS2-associated Rab5 guanine nucleotide exchange activity and its regulatory function on endosome trafficking.

Kunita R, Otomo A, Mizumura H, Suzuki K, Showguchi-Miyata J, Yanagisawa Y, Hadano S, Ikeda JE. Kunita R, et al. Among authors: ikeda je. J Biol Chem. 2004 Sep 10;279(37):38626-35. doi: 10.1074/jbc.M406120200. Epub 2004 Jul 7. J Biol Chem. 2004. PMID: 15247254 Free article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

122 results

Search Page