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Beneficial innate signaling interference for antibacterial responses by a Toll-like receptor-mediated enhancement of the MKP-IRF3 axis.
Negishi H, Matsuki K, Endo N, Sarashina H, Miki S, Matsuda A, Fukazawa K, Taguchi-Atarashi N, Ikushima H, Yanai H, Nishio J, Honda K, Fujioka Y, Ohba Y, Noda T, Taniguchi S, Nishida E, Zhang Y, Chi H, Flavell RA, Taniguchi T. Negishi H, et al. Among authors: ikushima h. Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):19884-9. doi: 10.1073/pnas.1320145110. Epub 2013 Nov 18. Proc Natl Acad Sci U S A. 2013. PMID: 24248350 Free PMC article.
Biology of transforming growth factor-β signaling.
Ikushima H, Miyazono K. Ikushima H, et al. Curr Pharm Biotechnol. 2011 Dec;12(12):2099-107. doi: 10.2174/138920111798808419. Curr Pharm Biotechnol. 2011. PMID: 21619537 Review.
Glioma-initiating cells retain their tumorigenicity through integration of the Sox axis and Oct4 protein.
Ikushima H, Todo T, Ino Y, Takahashi M, Saito N, Miyazawa K, Miyazono K. Ikushima H, et al. J Biol Chem. 2011 Dec 2;286(48):41434-41441. doi: 10.1074/jbc.M111.300863. Epub 2011 Oct 10. J Biol Chem. 2011. PMID: 21987575 Free PMC article.
We have previously reported that the transforming growth factor-beta (TGF-beta)-Sox4-Sox2 pathway is essential for glioma-initiating cells to retain their stemness, and inhibition of TGF-beta signaling may lead to differentiation of glioma-initiating cells (Ikushima, H …
We have previously reported that the transforming growth factor-beta (TGF-beta)-Sox4-Sox2 pathway is essential for glioma-initiating cells t …
144 results